Publication Name	World Journal of Diabetes
Manuscript ID	62278
Country	Chile

Received	2021-01-04 13:44
Peer-Review Started	2021-01-04 13:45
To Make the First Decision
Return for Revision	2021-01-25 01:13
Revised	2021-01-29 19:05
Second Decision	2021-04-07 12:34
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2021-04-07 20:52
Articles in Press	2021-04-07 20:52
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-04-23 01:54
Publish the Manuscript Online	2021-05-06 11:18

ISSN	1948-9358 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Medicine, Research & Experimental
Manuscript Type	Minireviews
Article Title	Advanced-glycation end-products axis: A contributor to the risk of severe illness from COVID-19 in diabetes patients
Manuscript Source	Invited Manuscript
All Author List	Armando Rojas, Cristian Lindner, Ileana Gonzàlez and Miguel Angel Morales
ORCID	Author(s) ORCID Number Armando Rojas http://orcid.org/0000-0001-9911-7142 Cristian Lindner http://orcid.org/0000-0002-2642-4288 Ileana Gonzàlez http://orcid.org/0000-0002-2488-9380 Miguel Angel Morales http://orcid.org/0000-0001-7698-9669
Funding Agency and Grant Number
Corresponding Author	Armando Rojas, PhD, Full Professor, Biomedical Research Labs, Medicine Faculty, Catholic University of Maule, 3605 San Miguel Avenue, Talca 3605, Chile. arojasr@ucm.cl
Key Words	COVID-19; Diabetes mellitus; Advanced glycation; Alarmins; Advanced-glycation end-products axis; Inflammation
Core Tip	Compelling evidences support that diabetes mellitus increases the risk of coronavirus disease 2019 complications, as well as the overall syndrome coronavirus 2 case-fatality. Different reports have suggested the putative involvement of several molecular mechanisms underlying this increased risk. We herein discuss the contribution of the activation of the receptor for advanced-glycation end-products axis to the higher risk for severe illness reported in diabetes patients with coronavirus disease 2019.
Publish Date	2021-05-06 11:18
Citation	Rojas A, Lindner C, Gonzàlez I, Morales MA. Advanced-glycation end-products axis: A contributor to the risk of severe illness from COVID-19 in diabetes patients. World J Diabetes 2021; 12(5): 590-602
URL	https://www.wjgnet.com/1948-9358/full/v12/i5/590.htm
DOI	https://dx.doi.org/10.4239/wjd.v12.i5.590

Full Article (PDF)	WJD-12-590.pdf
Full Article (Word)	WJD-12-590.docx
Manuscript File	62278_Auto_Edited_LM.docx
Answering Reviewers	62278-Answering reviewers.pdf
Audio Core Tip	62278-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	62278-Conflict-of-interest statement.pdf
Copyright License Agreement	62278-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	62278-Language certificate.pdf
Peer-review Report	62278-Peer-review(s).pdf
Scientific Misconduct Check	62278-Scientific misconduct check.pdf
Scientific Editor Work List	62278-Scientific editor work list.pdf
CrossCheck Report	62278-CrossCheck report.pdf