Publication Name	World Journal of Biological Chemistry
Manuscript ID	6241
Country	Canada

Received	2013-10-10 10:31
Peer-Review Started	2013-10-11 12:04
To Make the First Decision	2013-10-21 11:09
Return for Revision	2013-10-23 19:19
Revised	2013-12-11 03:03
Second Decision	2014-01-06 20:15
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-01-06 20:32
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-02-26 11:19
Publish the Manuscript Online	2014-03-19 21:35

ISSN	1949-8454 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Virology
Manuscript Type	Review
Article Title	Systems biology unravels interferon responses to respiratory virus infections
Manuscript Source	Invited Manuscript
All Author List	Andrea L Kroeker and Kevin M Coombs
Funding Agency and Grant Number
Corresponding Author	Kevin M Coombs, Professor, Department of Microbiology, University of Manitoba, 730 William Avenue Winnipeg, Winnipeg, MB R3E 0J9, Canada. kevin.coombs@med.umanitoba.ca
Key Words	Respiratory virus; Interferon; Systems biology; Proteomics; Genomics; Innate immunity
Core Tip	Many novel regulators of innate immune signalling pathways, such as the interferon signalling pathway, have been discovered recently. These advances may be in part attributed to high-throughput systems biology techniques including genomic, proteomic, miRNA and siRNA screens, as well as through various confirmatory methods using quantitative polymerase chain reaction, microscopy, and animal models. Collectively, these studies have provided insights into novel drug targets that could boost host innate immunity or could potentially serve as broad-spectrum anti-virals against RNA respiratory viruses.
Publish Date	2014-03-19 21:35
Citation	Kroeker AL, Coombs KM. Systems biology unravels interferon responses to respiratory virus infections. World J Biol Chem 2014; 5(1): 12-25 Available from: URL: http://www.wjgnet.com/1949-8454/full/v5/i1/12.htm DOI: http://dx.doi.org/10.4331/wjbc.v5.i1.12
URL	http://www.wjgnet.com/1949-8454/full/v5/i1/12.htm
DOI	http://dx.doi.org/10.4331/wjbc.v5.i1.12

Full Article (PDF)	wjbc-5-1.pdf
Full Article (Word)	wjbc-5-1.doc
Manuscript File	6241-Review.docx
Answering Reviewers	6241-Answering reviewers.pdf
Copyright License Agreement	6241-Copyright assignment.pdf
Peer-review Report	6241-Peer review(s).pdf
Scientific Editor Work List	6241-Scientific editor work list.doc