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Articles Published Processes
7/19/2021 2:10:40 PM | Browse: 734 | Download: 1603
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Received |
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2021-02-21 02:05 |
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Peer-Review Started |
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2021-02-21 02:08 |
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To Make the First Decision |
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Return for Revision |
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2021-05-13 00:36 |
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Revised |
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2021-05-16 22:33 |
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Second Decision |
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2021-07-07 12:57 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-07-07 13:53 |
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Articles in Press |
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2021-07-07 13:53 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-07-15 06:44 |
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Publish the Manuscript Online |
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2021-07-19 14:10 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Prognostic role of plasma level of angiopoietin-1, angiopoitin-2, and vascular endothelial growth factor in hepatocellular carcinoma
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Gwang Hyeon Choi, Eun Sun Jang, Jin-Wook Kim and Sook‐Hyang Jeong |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Seoul National University Bundang Hospital Research Fund |
02-2019-037 |
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| Corresponding Author |
Sook‐Hyang Jeong, PhD, Professor, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, 82 Gumi-ro 173 beon-gil, Bundang-gu, Seongnam-si, Gyeonggi-do, Seongnam 13620, South Korea. jsh@snubh.org |
| Key Words |
Hepatocellular carcinoma; Angiogenesis; Biomarker; Prognosis; Survival |
| Core Tip |
Most hepatocellular carcinomas (HCCs) are hypervascular tumor, thus angiogenesis markers can be a potential biomarker. This study explored the potential of each plasma level of angiopoietin (Ang)-1, Ang-2, and vascular endothelial growth factor as a prognostic biomarker for very early to advanced stages of HCC via detailed analysis in comparison with alpha-fetoprotein. The plasma level of Ang-2 correlated with liver function, tumor stage, and tumor invasiveness. Multivariable and propensity score-matched analyses revealed Ang-2 levels with the highest predictive power for overall survival in patients with HCC. |
| Publish Date |
2021-07-19 14:10 |
| Citation |
Choi GH, Jang ES, Kim JW, Jeong SH. Prognostic role of plasma level of angiopoietin-1, angiopoitin-2, and vascular endothelial growth factor in hepatocellular carcinoma. World J Gastroenterol 2021; 27(27): 4453-4467 |
| URL |
https://www.wjgnet.com/1007-9327/full/v27/i27/4453.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v27.i27.4453 |
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