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Articles Published Processes
4/9/2021 5:27:04 AM | Browse: 506 | Download: 598
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Received |
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2021-01-13 19:35 |
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Peer-Review Started |
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2021-01-13 19:35 |
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To Make the First Decision |
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Return for Revision |
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2021-02-12 06:04 |
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Revised |
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2021-02-23 22:26 |
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Second Decision |
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2021-03-23 09:04 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-03-24 07:53 |
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Articles in Press |
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2021-03-24 07:53 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-03-29 23:53 |
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Publish the Manuscript Online |
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2021-04-09 05:27 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Ophthalmology |
| Manuscript Type |
Minireviews |
| Article Title |
Malfunction of outer retinal barrier and choroid in the occurrence and progression of diabetic macular edema
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Ştefan Ţălu and Simona Delia Nicoara |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Simona Delia Nicoara, MD, PhD, Chief Doctor, Full Professor, Department of Ophthalmology, Iuliu Haţieganu University of Medicine and Pharmacy, 8 Victor Babes St, Cluj-Napoca 400441, Romania. simonanicoara1@gmail.com |
| Key Words |
Diabetic macular edema; External limiting membrane; Hyperreflective foci; Inner segment/outer segment line; Optical coherence tomography; Outer retinal barrier |
| Core Tip |
Progress in optical coherence tomography technology allowed the identification of new pathogenic pathways in diabetic macular edema (DME) involving the outer retina and underlying choroid. The presence of fluid in the subretinal space is suggestive for the alteration of the outer blood retinal barrier and responds better to intravitreal triamcinolone as compared to anti- vascular endothelial growth factor. The disruption of external limiting membrane (ELM) is associated with visual impairment being a predictor of poor outcomes following the treatment with triamcinolone. The integrity of ELM and of the inner segment/outer segment line was found to correlate positively with best corrected visual acuity in DME. |
| Publish Date |
2021-04-09 05:27 |
| Citation |
Ţălu Ş, Nicoara SD. Malfunction of outer retinal barrier and choroid in the occurrence and progression of diabetic macular edema. World J Diabetes 2021; 12(4): 437-452 |
| URL |
https://www.wjgnet.com/1948-9358/full/v12/i4/437.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v12.i4.437 |
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