Publication Name	World Journal of Gastroenterology
Manuscript ID	63097
Country	China

Received	2021-01-25 13:35
Peer-Review Started	2021-01-25 13:40
To Make the First Decision
Return for Revision	2021-02-27 22:59
Revised	2021-03-08 13:38
Second Decision	2021-05-27 08:50
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2021-05-27 09:46
Articles in Press	2021-05-27 09:46
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-06-03 22:44
Typeset the Manuscript	2021-06-30 04:02
Publish the Manuscript Online	2021-07-06 02:31

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Human immune repertoire in hepatitis B virus infection
Manuscript Source	Invited Manuscript
All Author List	Qiao Zhan, Jing-Hang Xu, Yan-Yan Yu, Emily Lo KK, Felicianna -, Hani El-Nezami and Zheng Zeng
ORCID	Author(s) ORCID Number Qiao Zhan http://orcid.org/0000-0001-7785-2373 Jing-Hang Xu http://orcid.org/0000-0001-8848-3876 Yan-Yan Yu http://orcid.org/0000-0002-7557-1305 Emily Lo KK http://orcid.org/0000-0001-9258-0716 Felicianna - http://orcid.org/0000-0003-1252-5667 Hani El-Nezami http://orcid.org/0000-0001-6700-4346 Zheng Zeng http://orcid.org/0000-0002-4997-4223
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China (General Program) 61972007 National Natural Science Foundation of China (General Program) 30671855 International Science & Technology Cooperation Program of China 2014DFR31200 National Science and Technology Major Project of China 2017ZX10202202
Corresponding Author	Zheng Zeng, MD, PhD, Chief Physician, Department of Infectious Diseases, Peking University First Hospital, No. 8 Xishiku Street, Xicheng District, Beijing 100034, China. zeng@bjmu.edu.cn
Key Words	Immune repertoire; T cell receptor; B cell receptor; Hepatitis B virus; Chronic viral infection; High throughput sequencing
Core Tip	Hepatitis B virus (HBV) cure depends on the activation of anti-HBV adaptive immune system. Immune repertoire sequencing is a novel technology to demonstrate the sum of human’s adaptive immune system. However, the immune repertoires in HBV infection are still dimness. We herein review the immune repertoire analysis methodology and provide a new insight into outcomes of HBV infection and vaccination.
Publish Date	2021-07-06 02:31
Citation	Zhan Q, Xu JH, Yu YY, Lo KK E, Felicianna, El-Nezami H, Zeng Z. Human immune repertoire in hepatitis B virus infection. World J Gastroenterol 2021; 27(25): 3790-3801
URL	https://www.wjgnet.com/1007-9327/full/v27/i25/3790.htm
DOI	https://dx.doi.org/10.3748/wjg.v27.i25.3790

Full Article (PDF)	WJG-27-3790.pdf
Full Article (Word)	WJG-27-3790.docx
Manuscript File	63097-Review-Filipodia MSCL.docx
Answering Reviewers	63097-Answering reviewers.pdf
Audio Core Tip	63097-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	63097-Conflict-of-interest statement.pdf
Copyright License Agreement	63097-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	63097-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	63097-Language certificate.pdf
Peer-review Report	63097-Peer-review(s).pdf
Scientific Misconduct Check	63097-CrossCheck.png
Scientific Misconduct Check	63097-Bing-Gong ZM-2.png
Scientific Misconduct Check	63097-Scientific misconduct check.pdf
Scientific Editor Work List	63097-Scientific editor work list.pdf
CrossCheck Report	63097-CrossCheck report.pdf