Publication Name	World Journal of Clinical Cases
Manuscript ID	63099
Country	China

Received	2021-01-24 13:51
Peer-Review Started	2021-01-24 13:59
To Make the First Decision
Return for Revision	2021-03-08 00:02
Revised	2021-03-12 12:37
Second Decision	2021-05-08 09:13
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2021-05-08 09:54
Articles in Press	2021-05-08 09:54
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-06-25 08:13
Typeset the Manuscript	2021-07-22 01:47
Publish the Manuscript Online	2021-07-28 01:52

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Critical Care Medicine
Manuscript Type	Case Report
Article Title	Malaria-associated secondary hemophagocytic lymphohistiocytosis: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Xiao Zhou and Mei-Li Duan
ORCID	Author(s) ORCID Number Xiao Zhou http://orcid.org/0000-0003-1352-2871 Mei-Li Duan http://orcid.org/0000-0001-5947-4938
Funding Agency and Grant Number
Corresponding Author	Mei-Li Duan, MD, PhD, Chief Doctor, Professor, Department of Critical Care Medicine, Beijing Friendship Hospital, Capital Medical University, No. 95 Yong'an Road, Xicheng District, Beijing 100054, China. dmeili@ccmu.edu.cn
Key Words	Fever; Malaria; Hemophagocytic lymphohistiocytosis; Secondary; Case report
Core Tip	We found an unexpected association between malaria and hemophagocytic lymphohistiocytosis (HLH) in this case. Literature on malaria-associated HLH is sparse. There are no similar cases reported in China. Through this case, we make the diagnosis based on HLH-2004 criteria and adopt new biomarkers to make the diagnosis of HLH. Through multidisciplinary treatment, the patient was discharged in normal physical condition. This case highlights the importance of early diagnosis and timely therapy of the primary disease to secondary HLH.
Publish Date	2021-07-28 01:52
Citation	Zhou X, Duan ML. Malaria-associated secondary hemophagocytic lymphohistiocytosis: A case report. World J Clin Cases 2021; 9(22): 6403-6409
URL	https://www.wjgnet.com/2307-8960/full/v9/i22/6403.htm
DOI	https://dx.doi.org/10.12998/wjcc.v9.i22.6403

Full Article (PDF)	WJCC-9-6403.pdf
Full Article (Word)	WJCC-9-6403.docx
CARE Checklist–2016	63099-CARE-Checklist–2016-revision.pdf
Manuscript File	63099_Auto_Edited-ZMG-Webster J[22889]-Clear.docx
Answering Reviewers	63099-Answering reviewers.pdf
Audio Core Tip	63099-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	63099-Conflict-of-interest statement.pdf
Copyright License Agreement	63099-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s)	63099-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate	63099-Language certificate.pdf
Peer-review Report	63099-Peer-review(s).pdf
Scientific Misconduct Check	63099-Scientific misconduct check.pdf
Scientific Editor Work List	63099-Scientific editor work list.pdf
CrossCheck Report	63099-CrossCheck report.pdf