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Articles Published Processes
7/26/2021 11:20:59 AM | Browse: 548 | Download: 964
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Received |
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2021-01-27 15:48 |
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Peer-Review Started |
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2021-01-27 15:54 |
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To Make the First Decision |
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Return for Revision |
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2021-03-07 03:02 |
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Revised |
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2021-03-17 13:40 |
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Second Decision |
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2021-07-02 08:01 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-07-02 11:55 |
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Articles in Press |
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2021-07-02 11:55 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-07-10 23:57 |
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Typeset the Manuscript |
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2021-07-21 11:20 |
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Publish the Manuscript Online |
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2021-07-26 11:20 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Minireviews |
| Article Title |
Genetic variant of cyclooxygenase-2 in gastric cancer: More inflammation and susceptibility
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Xuan-Ke Ji, Sailaja Vatsalya Madhurapantula, Gui He, Kun-Yan Wang, Chun-Hua Song, Jian-Ying Zhang and Kai-Juan Wang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
81373097 |
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| Corresponding Author |
Kai-Juan Wang, PhD, Professor, College of Public Health, Zhengzhou University, No. 100 Kexue Avenue, Zhengzhou 450001, Henan Province, China. kjwang@163.com |
| Key Words |
Cyclooxygenase-2; Inflammation; Genetic variant; Gastric cancer; Prostaglandin E2 |
| Core Tip |
The cyclooxygenase-2 (COX-2) is considered to be the key inducible enzyme in prostaglandins synthesis, and non-steroidal anti-inflammatory drugs can reduce the risk of malignant tumors digestive system by blocking the effect of COX-2. However, COX-2 inhibitors to prevent or treat gastric cancer may be limited because of their cardiovascular side effects. This review is helpful for early screening and further research to find new approaches to gastric cancer treatment by summarizing the association between whole COX-2 sequences variation and susceptibility of gastric cancer and synthesizing the new progress in the role of COX-2 in gastric carcinogenesis. |
| Publish Date |
2021-07-26 11:20 |
| Citation |
Ji XK, Madhurapantula SV, He G, Wang KY, Song CH, Zhang JY, Wang KJ. Genetic variant of cyclooxygenase-2 in gastric cancer: More inflammation and susceptibility. World J Gastroenterol 2021; 27(28): 4653-4666 |
| URL |
https://www.wjgnet.com/1007-9327/full/v27/i28/4653.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v27.i28.4653 |
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