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7/26/2021 11:20:59 AM | Browse: 416 | Download: 581
Publication Name World Journal of Gastroenterology
Manuscript ID 63362
Country China
Received
2021-01-27 15:48
Peer-Review Started
2021-01-27 15:54
To Make the First Decision
Return for Revision
2021-03-07 03:02
Revised
2021-03-17 13:40
Second Decision
2021-07-02 08:01
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-07-02 11:55
Articles in Press
2021-07-02 11:55
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-07-10 23:57
Typeset the Manuscript
2021-07-21 11:20
Publish the Manuscript Online
2021-07-26 11:20
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Minireviews
Article Title Genetic variant of cyclooxygenase-2 in gastric cancer: More inflammation and susceptibility
Manuscript Source Invited Manuscript
All Author List Xuan-Ke Ji, Sailaja Vatsalya Madhurapantula, Gui He, Kun-Yan Wang, Chun-Hua Song, Jian-Ying Zhang and Kai-Juan Wang
ORCID
Author(s) ORCID Number
Xuan-Ke Ji http://orcid.org/0000-0002-8972-814X
Sailaja Vatsalya Madhurapantula http://orcid.org/0000-0002-2829-5571
Gui He http://orcid.org/0000-0002-8113-5737
Kun-Yan Wang http://orcid.org/0000-0003-4660-1584
Chun-Hua Song http://orcid.org/0000-0001-6028-5923
Jian-Ying Zhang http://orcid.org/0000-0003-2938-9526
Kai-Juan Wang http://orcid.org/0000-0002-3300-9453
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81373097
Corresponding Author Kai-Juan Wang, PhD, Professor, College of Public Health, Zhengzhou University, No. 100 Kexue Avenue, Zhengzhou 450001, Henan Province, China. kjwang@163.com
Key Words Cyclooxygenase-2; Inflammation; Genetic variant; Gastric cancer; Prostaglandin E2
Core Tip The cyclooxygenase-2 (COX-2) is considered to be the key inducible enzyme in prostaglandins synthesis, and non-steroidal anti-inflammatory drugs can reduce the risk of malignant tumors digestive system by blocking the effect of COX-2. However, COX-2 inhibitors to prevent or treat gastric cancer may be limited because of their cardiovascular side effects. This review is helpful for early screening and further research to find new approaches to gastric cancer treatment by summarizing the association between whole COX-2 sequences variation and susceptibility of gastric cancer and synthesizing the new progress in the role of COX-2 in gastric carcinogenesis.
Publish Date 2021-07-26 11:20
Citation Ji XK, Madhurapantula SV, He G, Wang KY, Song CH, Zhang JY, Wang KJ. Genetic variant of cyclooxygenase-2 in gastric cancer: More inflammation and susceptibility. World J Gastroenterol 2021; 27(28): 4653-4666
URL https://www.wjgnet.com/1007-9327/full/v27/i28/4653.htm
DOI https://dx.doi.org/10.3748/wjg.v27.i28.4653
Full Article (PDF) WJG-27-4653.pdf
Full Article (Word) WJG-27-4653.docx
Manuscript File 63362_Auto_Edited-JPY_WangTQ.docx
Answering Reviewers 63362-Answering reviewers.pdf
Audio Core Tip 63362-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 63362-Conflict-of-interest statement.pdf
Copyright License Agreement 63362-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 63362-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 63362-Language certificate.pdf
Supplementary Material 63362-Supplementary material.zip
Peer-review Report 63362-Peer-review(s).pdf
Scientific Misconduct Check 63362-Scientific misconduct check.pdf
Scientific Editor Work List 63362-Scientific editor work list.pdf