Publication Name	World Journal of Diabetes
Manuscript ID	63858
Country	South Korea

Received	2021-02-10 02:03
Peer-Review Started	2021-02-10 02:07
To Make the First Decision
Return for Revision	2021-03-08 03:58
Revised	2021-03-23 07:59
Second Decision	2021-05-20 13:35
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2021-05-20 14:17
Articles in Press	2021-05-20 14:17
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-05-31 00:34
Publish the Manuscript Online	2021-06-04 13:47

ISSN	1948-9358 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Biochemistry & Molecular Biology
Manuscript Type	Review
Article Title	Mechanisms linking gut microbial metabolites to insulin resistance
Manuscript Source	Invited Manuscript
All Author List	Hye Rim Jang and Hui-Young Lee
ORCID	Author(s) ORCID Number Hye Rim Jang http://orcid.org/0000-0002-8205-1973 Hui-Young Lee http://orcid.org/0000-0002-3464-6382
Funding Agency and Grant Number	Funding Agency Grant Number National Research Foundation Funded by the Korean Ministry of Science NRF-2018M3A9F3056405 National Research Foundation Funded by the Korean Ministry of Science NRF-2020R1A2B5B01002789
Corresponding Author	Hui-Young Lee, DVM, PhD, Associate Professor, Laboratory of Mitochondrial and Metabolic Diseases, Department of Health Sciences and Technology, GAIHST, Gachon University, 155, Gaetbeol-ro, Yeonsu-gu, Incheon 21999, South Korea. hylee@gachon.ac.kr
Key Words	Insulin resistance; Skeletal muscle; Liver; Adipose tissue; Intestine; Gut bacterial metabolites
Core Tip	Since the gut microbiota has been implicated in host energy metabolism and metabolic diseases, understanding mechanisms linked to insulin resistance is a first step in discovery of new drugs and novel targets against metabolic diseases. Here, we review the mechanisms linking gut microbial metabolites to insulin resistance in major target tissues of insulin.
Publish Date	2021-06-04 13:47
Citation	Jang HR, Lee HY. Mechanisms linking gut microbial metabolites to insulin resistance. World J Diabetes 2021; 12(6): 730-744
URL	https://www.wjgnet.com/1948-9358/full/v12/i6/730.htm
DOI	https://dx.doi.org/10.4239/wjd.v12.i6.730

Full Article (PDF)	WJD-12-730.pdf
Full Article (Word)	WJD-12-730.docx
Manuscript File	63858_Auto_Edited-ZMG.docx
Answering Reviewers	63858-Answering reviewers.pdf
Audio Core Tip	63858-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	63858-Conflict-of-interest statement.pdf
Copyright License Agreement	63858-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	63858-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate	63858-Language certificate.pdf
Peer-review Report	63858-Peer-review(s).pdf
Scientific Misconduct Check	63858-Scientific misconduct check.pdf
Scientific Editor Work List	63858-Scientific editor work list.pdf
CrossCheck Report	63858-CrossCheck report.pdf