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Articles Published Processes
6/25/2021 9:46:23 AM | Browse: 584 | Download: 1628
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Received |
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2021-02-06 17:13 |
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Peer-Review Started |
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2021-02-06 17:18 |
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To Make the First Decision |
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Return for Revision |
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2021-03-14 04:30 |
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Revised |
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2021-03-22 18:23 |
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Second Decision |
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2021-05-25 14:50 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-05-25 15:09 |
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Articles in Press |
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2021-05-25 15:09 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-06-06 08:24 |
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Typeset the Manuscript |
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2021-06-22 00:29 |
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Publish the Manuscript Online |
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2021-06-25 09:46 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Control Study |
| Article Title |
Altered profiles of fecal bile acids correlate with gut microbiota and inflammatory responses in patients with ulcerative colitis
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Zhen-Huan Yang, Fang Liu, Xiao-Ran Zhu, Fei-Ya Suo, Zi-jun Jia and Shu-Kun Yao |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Key Technology Support Program during “12th Five-Year Plan” Period of China |
2014BAI08B00 |
| National Key Research and Development Plan for Precision Medicine Research |
2017YFC0910002 |
| Leap-forward Development Program for Beijing Biopharmaceutical Industry (G20) |
Z171100001717008 |
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| Corresponding Author |
Shu-Kun Yao, MD, Professor, Department of Gastroenterology, China-Japan Friendship Hospital, No. 2 Yinghua East Street, Chaoyang District, Beijing 100029, China. shukunyao@126.com |
| Key Words |
Ulcerative colitis; Gut microbiota; Bile acids; Takeda G-protein-coupled receptor 5; Vitamin D receptor |
| Core Tip |
This study comprehensively investigated the changes in gut microbiota and fecal bile acid profiles and analyzed the relationship between bile acids, gut microbiota and inflammation in patients with ulcerative colitis. It was demonstrated that fecal bile acid profiles are closely related to gut microbiota and serum inflammatory cytokines. Dysregulation of gut microbiota and altered constitution of fecal bile acids may participate in regulating inflammatory responses by the bile acid receptors Takeda G-protein-coupled receptor 5 and vitamin D receptor. |
| Publish Date |
2021-06-25 09:46 |
| Citation |
Yang ZH, Liu F, Zhu XR, Suo FY, Jia ZJ, Yao SK. Altered profiles of fecal bile acids correlate with gut microbiota and inflammatory responses in patients with ulcerative colitis. World J Gastroenterol 2021; 27(24): 3609-3629 |
| URL |
https://www.wjgnet.com/1007-9327/full/v27/i24/3609.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v27.i24.3609 |
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