| ISSN |
1948-9366 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Nutrition & Dietetics |
| Manuscript Type |
Review |
| Article Title |
Neoadjuvant treatment: A window of opportunity for nutritional prehabilitation in patients with pancreatic ductal adenocarcinoma
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Ilaria Trestini, Marco Cintoni, Emanuele Rinninella, Futura Grassi, Salvatore Paiella, Roberto Salvia, Emilio Bria, Carmelo Pozzo, Sergio Alfieri, Antonio Gasbarrini, Giampaolo Tortora, Michele Milella and Maria Cristina Mele |
| ORCID |
|
| Funding Agency and Grant Number |
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| Corresponding Author |
Marco Cintoni, MD, Doctor, Doctor, Scuola di Specializzazione in Scienza dell’Alimentazione, Università di Roma Tor Vergata, Viale Oxford 81, Roma 00133, Italy. marco.cintoni@gmail.com |
| Key Words |
Pancreatic cancer; Neoadjuvant treatment; Pancreatic cancer surgery; Nutritional status; Nutritional prehabilitation; Malnutrition |
| Core Tip |
Among pancreatic ductal adenocarcinoma (PDAC) patients with resectable or borderline resectable disease, as well as those with locally advanced disease, with a feasibility of surgical resection of up to 30%, neoadjuvant treatment (NAT) has become the standard of care. Besides, NAT may impair functional reserve and lead to nutritional depletion, which may affect therapeutic tolerance, postoperative outcomes or even prevent the possibility of surgery. The current review suggests that NAT timeframe may provide a valuable opportunity for nutritional prehabilitation program, to minimize the NAT-related nutritional derangements, increase patient’s capacity to complete planned therapy, promote tissue healing and enhance patient’s recovery, thus, potentially improve outcomes. |
| Publish Date |
2021-09-18 13:32 |
| Citation |
Trestini I, Cintoni M, Rinninella E, Grassi F, Paiella S, Salvia R, Bria E, Pozzo C, Alfieri S, Gasbarrini A, Tortora G, Milella M, Mele MC. Neoadjuvant treatment: A window of opportunity for nutritional prehabilitation in patients with pancreatic ductal adenocarcinoma. World J Gastrointest Surg 2021; 13(9): 885-903 |
| URL |
https://www.wjgnet.com/1948-9366/full/v13/i9/885.htm |
| DOI |
https://dx.doi.org/10.4240/wjgs.v13.i9.885 |
