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Articles Published Processes
7/21/2021 8:24:09 AM | Browse: 514 | Download: 1146
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Received |
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2021-02-10 12:09 |
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Peer-Review Started |
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2021-02-10 12:15 |
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To Make the First Decision |
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Return for Revision |
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2021-03-31 13:42 |
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Revised |
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2021-04-13 14:12 |
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Second Decision |
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2021-05-25 08:05 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-05-25 11:30 |
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Articles in Press |
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2021-05-25 11:30 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-06-06 08:25 |
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Typeset the Manuscript |
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2021-07-15 00:45 |
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Publish the Manuscript Online |
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2021-07-21 08:24 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Research status on immunotherapy trials of gastric cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Chao Liang, Heng-Miao Wu, Wei-Ming Yu and Wei Chen |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Funds of Young Scientists of China |
81802944 |
| Zhejiang Provincial Public Welfare Technology Application Research Project |
LGF18H160007 |
| Program of Ningbo Medical Research Center for Digestive System Cancer |
2019A21003 |
| Zhejiang Provincial Natural Science Foundation |
LR20H160001 |
| Zhejiang Provincial Ten Thousand Plan for Young Top Talents to Wei Chen (2018) |
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| Training Objects of Health Innovative Talents of Zhejiang Health to Wei Chen (2018) |
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| Key Project Co-constructed by Zhejiang Province and Ministry |
WKJ-ZJ-1916 |
| National Natural Science Foundation of China |
81972693 |
| National Natural Science Foundation of China |
81802383 |
| National Natural Science Foundation of China |
81972674 |
| National Natural Science Foundation of China |
81673809 |
| National Natural Science Foundation of China |
31900543 |
| Zhejiang Provincial Traditional Chinese Medicine Science and Technology Project |
2020ZZ004 |
| Projects of Lishui Key Research and Development Plan in Zhejiang Province |
2017ZDYF12 |
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| Corresponding Author |
Wei Chen, MD, PhD, Doctor, Doctor, Professor, Surgeon, Cancer Institute of Integrated Traditional Chinese and Western Medicine, Zhejiang Academy of Traditional Chinese Medicine, Tongde Hospital of Zhejiang Province, No. 234 Gucui Road, Hangzhou 310012, Zhejiang Province, China. viogro@163.com |
| Key Words |
Gastric cancer; Immunotherapy; Clinical trial; Immune checkpoint inhibitor; Neoadjuvant therapy |
| Core Tip |
Immune checkpoint inhibitors gigantically expand the methods of immunotherapy and bring a glimmer of hopefulness for patients with advanced gastric cancer (GC). Ongoing clinical trials show that the effect of monotherapy was not satisfactory, while the combination therapy manifested a better response rate. The most recent clinical trial results of GC immunotherapy have been reviewed, to suggest the reasons and mechanisms of the high response rate. Additionally, we have proposed the potential problems of these trials and speculated on the benefits of immune checkpoint inhibitors in neoadjuvant therapy. |
| Publish Date |
2021-07-21 08:24 |
| Citation |
Liang C, Wu HM, Yu WM, Chen W. Research status on immunotherapy trials of gastric cancer. World J Clin Cases 2021; 9(21): 5782-5793 |
| URL |
https://www.wjgnet.com/2307-8960/full/v9/i21/5782.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v9.i21.5782 |
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