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7/21/2021 8:24:09 AM | Browse: 378 | Download: 731
Publication Name World Journal of Clinical Cases
Manuscript ID 64146
Country/Territory China
Received
2021-02-10 12:09
Peer-Review Started
2021-02-10 12:15
To Make the First Decision
Return for Revision
2021-03-31 13:42
Revised
2021-04-13 14:12
Second Decision
2021-05-25 08:05
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-05-25 11:30
Articles in Press
2021-05-25 11:30
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-06-06 08:25
Typeset the Manuscript
2021-07-15 00:45
Publish the Manuscript Online
2021-07-21 08:24
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Minireviews
Article Title Research status on immunotherapy trials of gastric cancer
Manuscript Source Unsolicited Manuscript
All Author List Chao Liang, Heng-Miao Wu, Wei-Ming Yu and Wei Chen
ORCID
Author(s) ORCID Number
Chao Liang http://orcid.org/0000-0003-0613-1805
Heng-Miao Wu http://orcid.org/0000-0002-8670-5727
Wei-Ming Yu http://orcid.org/0000-0002-8925-0078
Wei Chen http://orcid.org/0000-0002-1919-5994
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Funds of Young Scientists of China 81802944
Zhejiang Provincial Public Welfare Technology Application Research Project LGF18H160007
Program of Ningbo Medical Research Center for Digestive System Cancer 2019A21003
Zhejiang Provincial Natural Science Foundation LR20H160001
Zhejiang Provincial Ten Thousand Plan for Young Top Talents to Wei Chen (2018)
Training Objects of Health Innovative Talents of Zhejiang Health to Wei Chen (2018)
Key Project Co-constructed by Zhejiang Province and Ministry WKJ-ZJ-1916
National Natural Science Foundation of China 81972693
National Natural Science Foundation of China 81802383
National Natural Science Foundation of China 81972674
National Natural Science Foundation of China 81673809
National Natural Science Foundation of China 31900543
Zhejiang Provincial Traditional Chinese Medicine Science and Technology Project 2020ZZ004
Projects of Lishui Key Research and Development Plan in Zhejiang Province 2017ZDYF12
Corresponding Author Wei Chen, MD, PhD, Doctor, Professor, Surgeon, Cancer Institute of Integrated Traditional Chinese and Western Medicine, Zhejiang Academy of Traditional Chinese Medicine, Tongde Hospital of Zhejiang Province, No. 234 Gucui Road, Hangzhou 310012, Zhejiang Province, China. viogro@163.com
Key Words Gastric cancer; Immunotherapy; Clinical trial; Immune checkpoint inhibitor; Neoadjuvant therapy
Core Tip Immune checkpoint inhibitors gigantically expand the methods of immunotherapy and bring a glimmer of hopefulness for patients with advanced gastric cancer (GC). Ongoing clinical trials show that the effect of monotherapy was not satisfactory, while the combination therapy manifested a better response rate. The most recent clinical trial results of GC immunotherapy have been reviewed, to suggest the reasons and mechanisms of the high response rate. Additionally, we have proposed the potential problems of these trials and speculated on the benefits of immune checkpoint inhibitors in neoadjuvant therapy.
Publish Date 2021-07-21 08:24
Citation Liang C, Wu HM, Yu WM, Chen W. Research status on immunotherapy trials of gastric cancer. World J Clin Cases 2021; 9(21): 5782-5793
URL https://www.wjgnet.com/2307-8960/full/v9/i21/5782.htm
DOI https://dx.doi.org/10.12998/wjcc.v9.i21.5782
Full Article (PDF) WJCC-9-5782.pdf
Full Article (Word) WJCC-9-5782.docx
Manuscript File 64146_Auto_Edited-JPY_WangTQ.docx
Answering Reviewers 64146-Answering reviewers.pdf
Audio Core Tip 64146-Audio core tip.aac
Conflict-of-Interest Disclosure Form 64146-Conflict-of-interest statement.pdf
Copyright License Agreement 64146-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 64146-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 64146-Copyright license agreement.pdf
Peer-review Report 64146-Peer-review(s).pdf
Scientific Misconduct Check 64146-Bing-Wang JL-1.jpg
Scientific Misconduct Check 64146-Bing-Fan JR-2.png
Scientific Misconduct Check 64146-Scientific misconduct check.pdf
Scientific Editor Work List 64146-Scientific editor work list.pdf