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Articles Published Processes
8/24/2021 2:06:59 AM | Browse: 498 | Download: 1097
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Received |
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2021-02-10 15:49 |
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Peer-Review Started |
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2021-02-10 15:53 |
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To Make the First Decision |
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Return for Revision |
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2021-03-15 13:49 |
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Revised |
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2021-03-31 12:47 |
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Second Decision |
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2021-07-06 10:04 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-07-06 10:34 |
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Articles in Press |
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2021-07-06 10:34 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-07-15 00:41 |
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Typeset the Manuscript |
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2021-08-16 15:07 |
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Publish the Manuscript Online |
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2021-08-24 02:06 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Opinion Review |
| Article Title |
Reconsideration of recurrence and metastasis in colorectal cancer
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Rui Wang, Qi Su and Zhao-Peng Yan |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| 345 Talent Project of Shengjing Hospital of China Medical University |
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| Corresponding Author |
Zhao-Peng Yan, MD, PhD, Associate Chief Physician, Associate Professor, Surgeon, Department of General Surgery, Shengjing Hospital of China Medical University, No. 36 Sanhao Street, Heping District, Shenyang 110004, Liaoning Province, China. yanzpus@outlook.com |
| Key Words |
Colorectal cancer; Cancer recurrence; Cancer dormancy; Metastasis; Cancer relapse |
| Core Tip |
In this work, we proposed the recurrence/metastasis of colorectal cancer consists of two types: recurrence from activation of dormant cancer cells and recurrence from proliferation of post-operative residual cancer cells. These two recurrences have their own unique mechanisms, biological behaviors, response to therapy, and prognosis. For type 1 recurrences, surgical resection should be considered. Type 2 recurrences should be managed systematically, in addition to surgical resection. Our theory also suggests that the tumor-node-metastasis staging system should be re-evaluated. |
| Publish Date |
2021-08-24 02:06 |
| Citation |
Wang R, Su Q, Yan ZP. Reconsideration of recurrence and metastasis in colorectal cancer. World J Clin Cases 2021; 9(24): 6964-6968 |
| URL |
https://www.wjgnet.com/2307-8960/full/v9/i24/6964.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v9.i24.6964 |
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