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Articles Published Processes
7/21/2021 8:24:09 AM | Browse: 364 | Download: 1053
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Received |
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2021-02-24 08:44 |
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Peer-Review Started |
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2021-02-24 08:48 |
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To Make the First Decision |
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Return for Revision |
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2021-04-18 04:29 |
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Revised |
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2021-05-02 02:22 |
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Second Decision |
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2021-05-26 12:33 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-05-26 13:03 |
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Articles in Press |
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2021-05-26 13:03 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-06-10 00:45 |
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Typeset the Manuscript |
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2021-07-14 05:32 |
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Publish the Manuscript Online |
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2021-07-21 08:24 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Infectious Diseases |
| Manuscript Type |
Case Control Study |
| Article Title |
Soluble programmed death-1 is predictive of HBsAg loss in chronic hepatitis B patients after antiviral treatment
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ning Tan, Hao Luo, Qian Kang, Jia-Li Pan, Ran Cheng, Hong-Li Xi, Hong-Yu Chen, Yi-Fan Han, Yu-Qing Yang and Xiao-Yuan Xu |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the 13th Five-Year Plan of Ministry of Science and Technology of the People’s Republic of China |
2017ZX10302201-004-009 |
| the 13th Five-Year Plan of Ministry of Science and Technology of the People’s Republic of China |
2017ZX10203202-003 |
| Beijing Municipal Science and Technology Commission of Major Projects |
D161100002716002 |
| Beijing Municipal Science and Technology Commission of Major Projects |
D161100002716003 |
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| Corresponding Author |
Xiao-Yuan Xu, MD, Chief Physician, Professor, Department of Infectious Diseases, Peking University First Hospital, No.8 Xishiku Street, Beijing 100034, China. xiaoyuanxu6@163.com |
| Key Words |
Programmed cell death 1 protein; Hepatitis B surface antigen; Chronic hepatitis B; Antiviral; Nucleos(t)ide analogs; Hepatitis B e antigen |
| Core Tip |
This study analyzed the data and samples from patients with chronic hepatitis B who underwent antiviral treatment and were followed up for 12 years to investigate the factors associated with hepatitis B surface antigen (HBsAg) loss and explore the impact of soluble programmed death-1 (sPD-1) levels. The sPD-1 Levels were significantly different between patients with and without HBsAg loss during antiviral treatment. The sPD-1 Levels at 6 mo can predict HBsAg loss after 12 years of antiviral treatment. |
| Publish Date |
2021-07-21 08:24 |
| Citation |
Tan N, Luo H, Kang Q, Pan JL, Cheng R, Xi HL, Chen HY, Han YF, yang YP, Xu XY. Soluble programmed death-1 is predictive of HBsAg loss in chronic hepatitis B patients after antiviral treatment . World J Clin Cases 2021; 9(21): 5812-5821 |
| URL |
https://www.wjgnet.com/2307-8960/full/v9/i21/5812.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v9.i21.5812 |
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