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Articles Published Processes
1/20/2022 10:47:59 AM | Browse: 403 | Download: 927
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Received |
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2021-02-26 15:53 |
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Peer-Review Started |
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2021-02-26 15:57 |
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To Make the First Decision |
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Return for Revision |
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2021-06-16 04:06 |
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Revised |
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2021-07-07 17:14 |
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Second Decision |
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2022-01-04 03:26 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-01-05 03:01 |
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Articles in Press |
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2022-01-05 03:01 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-01-06 08:04 |
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Publish the Manuscript Online |
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2022-01-20 10:47 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Biochemistry & Molecular Biology |
| Manuscript Type |
Minireviews |
| Article Title |
Epigenetic regulation by long noncoding RNAs in osteo-/adipogenic differentiation of mesenchymal stromal cells and degenerative bone diseases
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Kai Xia, Li-Yuan Yu, Xin-Qi Huang, Zhi-He Zhao and Jun Liu |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China (General Program) |
81870743 |
| National Natural Science Foundation of China (General Program) |
81771048 |
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| Corresponding Author |
Jun Liu, DDS, PhD, Professor, State Key Laboratory of Oral Diseases & National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, No. 14, 3rd Section, South Renmin Road, Chengdu 610041, Sichuan Province, China. junliu@scu.edu.cn |
| Key Words |
Long noncoding RNA; Epigenetics; DNA methylation; Histones; Cell differentiation; Bone diseases |
| Core Tip |
In this review, we summarized the roles of long noncoding RNAs (lncRNAs) played in mesenchymal stromal cells (MSCs) differentiation and common degenerative bone diseases through reciprocal interactions between lncRNAs and epigenetic modifiers, focusing on the most common epigenetic mechanisms: DNA methylation and histone modifications. It is our hope that this review may provide an updated summary that sheds light on the lncRNA-based precise regulation of the MSC differentiation process and highlights possible therapeutic targets of degenerative bone diseases. |
| Publish Date |
2022-01-20 10:47 |
| Citation |
Xia K, Yu LY, Huang XQ, Zhao ZH, Liu J. Epigenetic regulation by long noncoding RNAs in osteo-/adipogenic differentiation of mesenchymal stromal cells and degenerative bone diseases. World J Stem Cells 2022; 14(1): 92-103 |
| URL |
https://www.wjgnet.com/1948-0210/full/v14/i1/92.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v14.i1.92 |
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