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Articles Published Processes
9/22/2021 8:09:41 AM | Browse: 558 | Download: 1083
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Received |
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2021-02-23 17:19 |
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Peer-Review Started |
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2021-02-23 17:27 |
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To Make the First Decision |
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Return for Revision |
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2021-05-03 00:59 |
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Revised |
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2021-05-04 06:42 |
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Second Decision |
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2021-08-05 03:21 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-08-05 08:37 |
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Articles in Press |
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2021-08-05 08:37 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-08-14 18:41 |
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Typeset the Manuscript |
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2021-09-16 10:49 |
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Publish the Manuscript Online |
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2021-09-22 08:09 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Biology |
| Manuscript Type |
Review |
| Article Title |
Epigenetic mechanisms of liver tumor resistance to immunotherapy
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Julie Sanceau and Angélique Gougelet |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Ligue Nationale Contre le Cancer and the Agence Nationale de la Recherche |
DLK1-EPILIV 2018-2021 |
| Université de Paris |
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| Corresponding Author |
Angélique Gougelet, PhD, Research Scientist, Centre de Recherche des Cordeliers, Sorbonne Université, Inserm, Université de Paris, 15 Rue de L'école de Médecine, Paris 75006, France. angelique.gougelet@inserm.fr |
| Key Words |
Liver cancer; Immunotherapies; Epigenetics; Resistance; Hepatocellular carcinoma |
| Core Tip |
Although our understanding of hepatocellular carcinoma (HCC) pathogenesis has improved, this aggressive tumor is still devoid of effective treatments and remains a major health problem. Despite the justified hopes on immunotherapies, only a limited number of HCC patients respond to treatments. The characterization of the molecular mechanisms displayed by tumor cells to evade immune response will help to consider new combinations of therapies. The recent years, growing body of evidence argue for a modulation of tumor immune privilege by several epigenetic events and renders drugs targeting these regulators as a partner of choice for immunotherapy combination strategies. |
| Publish Date |
2021-09-22 08:09 |
| Citation |
Sanceau J, Gougelet A. Epigenetic mechanisms of liver tumor resistance to immunotherapy. World J Hepatol 2021; 13(9): 979-1002 |
| URL |
https://www.wjgnet.com/1948-5182/full/v13/i9/979.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v13.i9.979 |
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