Publication Name	World Journal of Clinical Cases
Manuscript ID	64903
Country	India

Received	2021-02-25 05:01
Peer-Review Started	2021-02-25 05:04
To Make the First Decision
Return for Revision	2021-05-13 06:00
Revised	2021-05-18 10:36
Second Decision	2021-08-17 03:18
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-08-17 13:17
Articles in Press	2021-08-17 13:17
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-09-28 10:07
Typeset the Manuscript	2021-10-26 01:19
Publish the Manuscript Online	2021-10-29 12:16

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non-Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Review
Article Title	Pharmaconutrition strategy to resolve SARS-CoV-2-induced inflammatory cytokine storm in non-alcoholic fatty liver disease: Omega-3 Long-chain polyunsaturated fatty acids
Manuscript Source	Invited Manuscript
All Author List	Shanmugam M Jeyakumar and Ayyalasomayajula Vajreswari
ORCID	Author(s) ORCID Number Shanmugam M Jeyakumar http://orcid.org/0000-0002-4500-8431 Ayyalasomayajula Vajreswari http://orcid.org/0000-0002-9465-9994
Funding Agency and Grant Number
Corresponding Author	Shanmugam M Jeyakumar, PhD, Senior Scientist, Department of Clinical Pharmacology, ICMR-National Institute for Research in Tuberculosis, No.1, Sathiyamoorthy Road, Chetpet , Chennai 600031, Tamil Nadu, India. smjkumar@gmail.com
Key Words	Lipids; Virus; Inflammation; Infection; Fish oil; Supplementation
Core Tip	Inflammatory cytokine storm seems to pose a risk for patients with non-alcoholic fatty liver disease (NAFLD), as these patients have shown severe coronavirus disease (COVID-19) than without NAFLD, while, liver injury has been reported high among COVID-19 patients. Thus, this bi-directional relationship between NAFLD and COVID-19 may worsen both the conditions at least in the subset of patients. Therefore, resolving the inflammatory cytokine storm is an important target, not only in the management of NAFLD but also for COVID-19. In this context, here we highlight the pharmacological potential of omega-3 Long-chain polyunsaturated fatty acids in the clinical nutrition therapy strategy to resolve inflammatory cytokine storm and its associated tissue injury.
Publish Date	2021-10-29 12:16
Citation	Jeyakumar SM, Vajreswari A. Pharmaconutrition strategy to resolve SARS-CoV-2-induced inflammatory cytokine storm in non-alcoholic fatty liver disease: Omega-3 Long-chain polyunsaturated fatty acids. World J Clin Cases 2021; 9(31): 9333-9349
URL	https://www.wjgnet.com/2307-8960/full/v9/i31/9333.htm
DOI	https://dx.doi.org/10.12998/wjcc.v9.i31.9333

Full Article (PDF)	WJCC-9-9333.pdf
Full Article (Word)	WJCC-9-9333.docx
Manuscript File	64903_Auto_Edited-ZMG-Webster J_JEYAKUMAR SM[24775]-Clear.doc
Answering Reviewers	64903-Answering reviewers.pdf
Audio Core Tip	64903-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	64903-Conflict-of-interest statement.pdf
Copyright License Agreement	64903-Copyright license agreement.pdf
Peer-review Report	64903-Peer-review(s).pdf
Scientific Misconduct Check	64903-Scientific misconduct check.pdf
Scientific Editor Work List	64903-Scientific editor work list.pdf