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Articles Published Processes
11/19/2021 9:32:33 AM | Browse: 502 | Download: 764
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Received |
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2021-02-26 09:44 |
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Peer-Review Started |
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2021-03-02 00:54 |
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To Make the First Decision |
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Return for Revision |
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2021-07-27 06:16 |
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Revised |
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2021-08-02 09:37 |
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Second Decision |
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2021-11-04 03:12 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-11-04 23:11 |
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Articles in Press |
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2021-11-04 23:11 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-11-17 09:25 |
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Publish the Manuscript Online |
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2021-11-19 09:32 |
ISSN |
2218-4333 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Oncology |
Manuscript Type |
Review |
Article Title |
Modulation of the immune response by heterogeneous monocytes and dendritic cells in lung cancer
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Manuscript Source |
Invited Manuscript |
All Author List |
Iwona Kwiecień, Elżbieta Rutkowska, Agata Raniszewska, Piotr Rzepecki and Joanna Domagała-Kulawik |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Military Institute of Medicine |
559 |
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Corresponding Author |
Iwona Kwiecień, MSc, PhD, Research Scientist, Department of Internal Medicine and Hematology, Laboratory of Hematology and Flow Cytometry, Military Institute of Medicine, Szaserów 128 Street, Warsaw 04-141, Poland. ikwiecien@wim.mil.pl |
Key Words |
Lung cancer; Dendritic cell; Monocyte; Tumour microenvironment; Cancer immunotherapy; Dendritic-cell vaccination |
Core Tip |
Monocytes and dendritic cells (DCs) as heterogeneous subpopulations may play a key role in the modulation of the immune response in malignant tumours. Monocytes may have a pro- and anti-tumour function and may differentiate into monocyte-derived DC. DCs have the properties of antigen presenting cells (APCs). These cells show a different phenotype depending on their maturity and on the influence of the tumour microenvironment. The DCs are of growing interest for their possible beneficial effects in lung cancer immunotherapy. This review highlights specific DC subpopulations in the anti-tumour response and summarizes the latest ongoing DC clinical trials in lung cancer. |
Publish Date |
2021-11-19 09:32 |
Citation |
Kwiecień I, Rutkowska E, Raniszewska A, Rzepecki P, Domagała-Kulawik J. Modulation of the immune response by heterogeneous monocytes and dendritic cells in lung cancer. World J Clin Oncol 2021; 12(11): 966-982 |
URL |
https://www.wjgnet.com/2218-4333/full/v12/i11/966.htm |
DOI |
https://dx.doi.org/10.5306/wjco.v12.i11.966 |
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