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Articles Published Processes
7/23/2021 1:30:22 PM | Browse: 480 | Download: 1149
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Received |
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2021-02-27 15:28 |
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Peer-Review Started |
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2021-02-27 15:34 |
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To Make the First Decision |
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Return for Revision |
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2021-04-06 01:02 |
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Revised |
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2021-04-20 05:51 |
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Second Decision |
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2021-06-22 14:11 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-06-22 14:35 |
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Articles in Press |
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2021-06-22 14:35 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-07-01 04:20 |
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Typeset the Manuscript |
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2021-07-22 05:51 |
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Publish the Manuscript Online |
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2021-07-23 13:30 |
ISSN |
1948-0210 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Biochemistry & Molecular Biology |
Manuscript Type |
Review |
Article Title |
Effects of shear stress on differentiation of stem cells into endothelial cells
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Manuscript Source |
Invited Manuscript |
All Author List |
Yan Huang, Jia-Yi Qian, Hong Cheng and Xiao-Ming Li |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Key R&D Program of China |
2017YFC1104703 |
National Natural Science Foundation of China |
11302020 |
National Natural Science Foundation of China |
31771042 |
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Corresponding Author |
Xiao-Ming Li, PhD, Professor, Beijing Advanced Innovation Centre for Biomedical Engineering, Key Laboratory for Biomechanics and Mechanobiology of Chinese Education Ministry, School of Biological Science and Medical Engineering, Beihang University, No. 37 Xueyuan Road, Haidian District, Beijing 100083, China. x.m.li@hotmail.com |
Key Words |
Shear stress; Stem cells; Cell differentiation; Endothelial cells; Mechanotransduction |
Core Tip |
Stem cells and shear stress are very important for the success of stem cell-based therapy for vascular diseases. This review highlights current data supporting the role of shear stress in stem cell differentiation into endothelial cells. Further, potential mechanisms and signaling cascades for transducing shear stress into a biological signal are proposed. Further study of stem cell responses to shear stress is necessary to apply stem cells for pharmacological applications and cardiovascular implants in the realm of regenerative medicine. |
Publish Date |
2021-07-23 13:30 |
Citation |
Huang Y, Qian JY, Cheng H, Li XM. Effects of shear stress on differentiation of stem cells into endothelial cells. World J Stem Cells 2021; 13(7): 894-913 |
URL |
https://www.wjgnet.com/1948-0210/full/v13/i7/894.htm |
DOI |
https://dx.doi.org/10.4252/wjsc.v13.i7.894 |
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