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8/20/2021 5:46:25 AM | Browse: 374 | Download: 861
Publication Name World Journal of Stem Cells
Manuscript ID 65098
Country Spain
Received
2021-02-28 00:31
Peer-Review Started
2021-02-28 00:31
To Make the First Decision
Return for Revision
2021-04-19 20:11
Revised
2021-05-03 06:54
Second Decision
2021-07-14 03:33
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-07-14 08:09
Articles in Press
2021-07-14 08:09
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-07-23 06:09
Typeset the Manuscript
2021-08-19 01:58
Publish the Manuscript Online
2021-08-20 05:46
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Research & Experimental Medicine
Manuscript Type Minireviews
Article Title Methods to produce induced pluripotent stem cell-derived mesenchymal stem cells: Mesenchymal stem cells from induced pluripotent stem cells
Manuscript Source Invited Manuscript
All Author List Victoria Dupuis and Elisa Oltra
ORCID
Author(s) ORCID Number
Victoria Dupuis http://orcid.org/0000-0001-6098-7757
Elisa Oltra http://orcid.org/0000-0003-0598-2907
Funding Agency and Grant Number
Corresponding Author Elisa Oltra, PhD, Full Professor, Department of Pathology, Universidad Católica de Valencia San Vicente Mártir, C/Quevedo 2, Valencia 46001, Spain. elisa.oltra@ucv.es
Key Words Mesenchymal stem cells; Induced pluripotent stem cell; Mesenchymal stem cells derived from induced pluripotent stem cells; Differentiation methods; Culture components; Mesenchymal stem cell markers
Core Tip Heterogeneity of mesenchymal stem cells (MSCs) quality might have hampered the robust success of stem-cell clinical trials (CTs). The production of MSCs from a single homogeneous source (i.e., induced pluripotent stem cells, iPSCs) could elevate stem-cell therapeutics standardization to unprecedented levels. However, a unique optimized procedure for large-scale production of MSCs, of homogenous quality, from iPSCs (iMSCs) is missing. Main methods, culture components, and common MSC markers to produce iMSCs are provided here as reference resources for the establishment of harmonized GMPs (Good Manufacturing Procedures) towards obtaining clinical grade iMSCs with improved CT performance.
Publish Date 2021-08-20 05:46
Citation Dupuis V, Oltra E. Methods to produce induced pluripotent stem cell-derived mesenchymal stem cells: Mesenchymal stem cells from induced pluripotent stem cells. World J Stem Cells 2021; 13(8): 1094-1111
URL https://www.wjgnet.com/1948-0210/full/v13/i8/1094.htm
DOI https://dx.doi.org/10.4252/wjsc.v13.i8.1094
Full Article (PDF) WJSC-13-1094.pdf
Full Article (Word) WJSC-13-1094.docx
Manuscript File 65098-Review-Filipodia.docx
Answering Reviewers 65098-Answering reviewers.pdf
Audio Core Tip 65098-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 65098-Conflict-of-interest statement.pdf
Copyright License Agreement 65098-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 65098-Language certificate.pdf
Supplementary Material 65098-Supplementary material.pdf
Peer-review Report 65098-Peer-review(s).pdf
Scientific Misconduct Check 65098-Scientific misconduct check.pdf
Scientific Editor Work List 65098-Scientific editor work list.pdf