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Articles Published Processes
9/18/2021 9:35:02 AM | Browse: 474 | Download: 917
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Received |
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2021-02-28 11:25 |
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Peer-Review Started |
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2021-02-28 11:27 |
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To Make the First Decision |
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Return for Revision |
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2021-04-19 18:41 |
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Revised |
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2021-04-29 08:49 |
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Second Decision |
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2021-08-13 02:57 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-08-13 07:00 |
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Articles in Press |
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2021-08-13 07:00 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-09-17 01:41 |
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Publish the Manuscript Online |
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2021-09-18 09:35 |
ISSN |
1948-0210 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Cell Biology |
Manuscript Type |
Minireviews |
Article Title |
Empty nose syndrome pathogenesis and cell-based biotechnology products as a new option for treatment
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Manuscript Source |
Invited Manuscript |
All Author List |
Inna M Gordiienko, Olga S Gubar, Roman Sulik, Taras Kunakh, Igor Zlatskiy and Alona Zlatska |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Igor Zlatskiy, PhD, Senior Researcher, State Institute of Genetic and Regenerative Medicine, National Academy of Medical Sciences of Ukraine, 67 Vyshgorodska Str., Kyiv 04114, Ukraine. zlatskiy@ukr.net |
Key Words |
Empty nose syndrome; Stem-cell-based technologies; Implants biomaterials; Grafts; Hydrogels; Mesenchymal stem cells |
Core Tip |
Empty nose syndrome is a complex disease, which pathogenesis is associated not only with changes in the architecture of the nasal passages, but also with changes in the receptor status of the nasal mucosa and disorders of perception of external stimuli at the systemic level. Due to the lack of effective convencial protocols for the treatment of this disease, there is a need to find new approaches to restoring the normal structure of the architecture of the nasal passages and return the functionality of the nasal mucosa. In addition, the proposed methods should be minimally invasive, implemented by injection. The advancement of regenerative medicine and biotechnology contributes to the development of new cell-based products in combination with various materials, which in the future will be able to help develop protocols for treatment patients with empty nose syndrome. |
Publish Date |
2021-09-18 09:35 |
Citation |
Gordiienko IM, Gubar OS, Sulik R, Kunakh T, Zlatskiy I, Zlatska A. Empty nose syndrome pathogenesis and cell-based biotechnology products as a new option for treatment. World J Stem Cells 2021; 13(9): 1293-1306 |
URL |
https://www.wjgnet.com/1948-0210/full/v13/i9/1293.htm |
DOI |
https://dx.doi.org/10.4252/wjsc.v13.i9.1293 |
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