Publication Name	World Journal of Clinical Cases
Manuscript ID	65158
Country	Greece

Received	2021-02-28 18:42
Peer-Review Started	2021-02-28 18:46
First Decision by Editorial Office Director	2021-04-18 02:22
Return for Revision	2021-04-19 13:19
Revised	2021-04-22 18:39
Publication Fee Transferred
Second Decision by Editor	2021-05-10 09:27
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2021-05-10 09:43
Articles in Press	2021-05-10 09:43
Edit the Manuscript by Language Editor	2021-05-18 19:40
Typeset the Manuscript	2021-06-25 09:28
Publish the Manuscript Online	2021-07-07 08:39

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Esophageal manifestation in patients with scleroderma
Manuscript Source	Invited Manuscript
All Author List	Theodoros A Voulgaris and Georgios P Karamanolis
ORCID	Author(s) ORCID Number Theodoros A Voulgaris http://orcid.org/0000-0002-8383-825X Georgios P Karamanolis http://orcid.org/0000-0001-9872-1276
Funding Agency and Grant Number
Corresponding Author	Georgios P Karamanolis, MD, PhD, Assistant Professor, Department of Gastroenterology and Hepatology, Laiko General Hospital, National and Kapodistian University of Athens, Michalakopoulou 176, Athens 11527, Greece. georgekaramanolis@yahoo.co.uk
Key Words	Systemic sclerosis; Esophagus; Gastroesophageal reflux disease; Esophageal dysmotility; Proton pump inhibitors
Core Tip	Gastrointestinal (GI) manifestations of systemic sclerosis (SSc), a rare autoimmune disease, are the most commonly encountered complications of the disease affecting nearly 90% of the SSc population. Among the GI tract, the esophagus is the most commonly affected. In this review, we will present the current understanding of the pathophysiologic mechanisms of SSc, the clinical presentation and diagnosis of esophageal involvement. Finally, we highlight the latest developments in the management of this disease.
Publish Date	2021-07-07 08:39
Citation	Voulgaris TA, Karamanolis GP. Esophageal manifestation in patients with scleroderma. World J Clin Cases 2021; 9(20): 5408-5419
URL	https://www.wjgnet.com/2307-8960/full/v9/i20/5408.htm
DOI	https://dx.doi.org/10.12998/wjcc.v9.i20.5408

Full Article (PDF)	WJCC-9-5408.pdf
Full Article (Word)	WJCC-9-5408.docx