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Articles Published Processes
6/4/2021 1:47:10 PM | Browse: 427 | Download: 837
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Received |
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2021-02-28 20:47 |
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Peer-Review Started |
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2021-02-28 20:54 |
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To Make the First Decision |
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Return for Revision |
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2021-03-30 02:04 |
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Revised |
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2021-04-05 14:17 |
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Second Decision |
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2021-05-20 13:38 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-05-20 14:24 |
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Articles in Press |
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2021-05-20 14:24 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-05-27 05:09 |
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Publish the Manuscript Online |
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2021-06-04 13:47 |
ISSN |
1948-9358 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Medicine, General & Internal |
Manuscript Type |
Minireviews |
Article Title |
Cardiovascular autonomic neuropathy in diabetes: Pathophysiology, clinical assessment and implications
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Manuscript Source |
Invited Manuscript |
All Author List |
Alice Duque, Mauro Felippe Felix Mediano, Andrea De Lorenzo and Luiz Fernando Rodrigues Jr |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Andrea De Lorenzo, PhD, Professor, Education and Research Department, Instituto Nacional de Cardiologia, Rua das Laranjeiras 374, Rio de Janeiro 22240006, RJ, Brazil. andlorenzo@hotmail.com |
Key Words |
Cardiovascular autonomic neuropathy; Cardiac autonomic neuropathy; Diabetes mellitus; Heart rate variability; Sympathetic autonomic nervous system; Parasympathetic autonomic nervous system |
Core Tip |
Cardiovascular autonomic neuropathy (CAN) is an important risk factor for cardiovascular events. However, CAN may be subclinical for several years, worsening its potential contribution to increased mortality due to late diagnosis. Even during the subclinical stage, CAN could be detected through reduction in heart rate variability, a non-invasive test. Therefore, considering that diabetes mellitus is a global epidemic and that diabetic neuropathy is the most common chronic complication of diabetes, the early identification and treatment of CAN could be a key point to mitigate the morbidity and mortality impact from this long-lasting condition. |
Publish Date |
2021-06-04 13:47 |
Citation |
Duque A, Mediano MFF, De Lorenzo A, Rodrigues Jr LF. Cardiovascular autonomic neuropathy in diabetes: Pathophysiology, clinical assessment and implications. World J Diabetes 2021; 12(6): 855-867 |
URL |
https://www.wjgnet.com/1948-9358/full/v12/i6/855.htm |
DOI |
https://dx.doi.org/10.4239/wjd.v12.i6.855 |
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