| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Mycology |
| Manuscript Type |
Editorial |
| Article Title |
<Italic>Exophiala dermatitidis</Italic>
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Daisuke Usuda, Toshihiro Higashikawa, Yuta Hotchi, Kenki Usami, Shintaro Shimozawa, Shungo Tokunaga, Ippei Osugi, Risa Katou, Sakurako Ito, Toshihiko Yoshizawa, Suguru Asako, Kentaro Mishima, Akihiko Kondo, Keiko Mizuno, Hiroki Takami, Takayuki Komatsu, Jiro Oba, Tomohisa Nomura and Manabu Sugita |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Daisuke Usuda, MD, MSc, PhD, Doctor, Doctor, Lecturer, Emergency and Critical Care Medicine, Juntendo University Nerima Hospital, 3-1-10 Takanodai, Nerima-ku 177-8521, Tokyo, Japan. d.usuda.qa@juntendo.ac.jp |
| Key Words |
Exophiala dermatitidis; Black yeast; Immunocompromised host; Matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry; Ribosomal ribonucleic acid; Antifungal drugs |
| Core Tip |
Exophiala is a genus comprising several species of opportunistic black yeasts, which belongs to Ascomycotina, and it is a rare cause of fungal infections. The final identification of this organism should be achieved through a combination of several methods, including the newly introduced diagnostic analysis, matrix-assisted laser desorption/ionization-time-of-flight mass spectrometry, together with sequencing of the ribosomal ribonucleic acid internal transcribed spacer region of the fungi, and histological and culture findings. Most forms of disease caused by this pathogen require aggressive combination therapies: both surgical intervention and aggressive antifungal therapy with novel compounds and azoles are necessary for effective treatment. Today, detailed knowledge regarding this pathogen is scarce, so further studies are required in order to collect evidence. |
| Publish Date |
2021-09-16 08:48 |
| Citation |
Usuda D, Higashikawa T, Hotchi Y, Usami K, Shimozawa S, Tokunaga S, Osugi I, Katou R, Ito S, Yoshizawa T, Asako S, Mishima K, Kondo A, Mizuno K, Takami H, Komatsu T, Oba J, Nomura T, Sugita M. Exophiala dermatitidis. World J Clin Cases 2021; 9(27): 7963-7972 |
| URL |
https://www.wjgnet.com/2307-8960/full/v9/i27/7963.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v9.i27.7963 |
