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Articles Published Processes
8/24/2021 2:07:00 AM | Browse: 412 | Download: 1167
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Received |
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2021-03-05 08:37 |
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Peer-Review Started |
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2021-03-05 08:46 |
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To Make the First Decision |
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Return for Revision |
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2021-04-24 04:14 |
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Revised |
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2021-04-27 11:54 |
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Second Decision |
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2021-07-15 03:23 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-07-15 06:31 |
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Articles in Press |
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2021-07-15 06:31 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-08-09 02:05 |
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Publish the Manuscript Online |
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2021-08-24 02:07 |
ISSN |
2307-8960 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Respiratory System |
Manuscript Type |
Case Report |
Article Title |
Therapy-related myeloid leukemia during erlotinib treatment in a non-small cell lung cancer patient: A case report
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
So-My Koo, Ki-Up Kim, Yang-Ki Kim and Soo-Taek Uh |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Soonchunhyang University Research Fund |
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Corresponding Author |
Ki-Up Kim, MD, Professor, Department of Internal Medicine, Soonchunhyang University Seoul Hospital, 59 Daesakwan-Ro, Yongsan-Ku, Seoul 04401, South Korea. kukim@schmc.ac.kr |
Key Words |
Acute myeloid leukemia; Erlotinib; Neoplasm, second primary; Non-small cell lung cancer; Case report |
Core Tip |
Therapy-related acute myeloid leukemia (t-AML) developed during erlotinib treatment in a patient with epidermal growth factor receptor (EGFR)–mutant advanced non-small cell lung cancer (NSCLC). Alkylating cytotoxic drugs and radiotherapy are common treatments for patients with NSCLC. Cases of t-AML related to alkylating agents typically have a long latency period. Since it was 20 mo in this case, EGFR–tyrosine kinase inhibitor (EGFR-TKI) usage may be related to or hasten AML development in patients who previously received cytotoxic chemotherapy. Although the mechanism remains unclear, when a patient takes an EGFR-TKI, t-AML development should be considered, especially if cytopenia persists. |
Publish Date |
2021-08-24 02:07 |
Citation |
Koo SM, Kim KU, Kim YK, Uh ST. Therapy-related myeloid leukemia during erlotinib treatment in a non-small cell lung cancer patient: A case report. World J Clin Cases 2021; 9(24): 7205-7211 |
URL |
https://www.wjgnet.com/2307-8960/full/v9/i24/7205.htm |
DOI |
https://dx.doi.org/10.12998/wjcc.v9.i24.7205 |
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