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Articles Published Processes
7/10/2021 10:08:34 AM | Browse: 602 | Download: 1264
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Received |
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2021-03-06 06:06 |
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Peer-Review Started |
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2021-03-06 06:10 |
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To Make the First Decision |
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Return for Revision |
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2021-04-19 03:08 |
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Revised |
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2021-04-20 08:39 |
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Second Decision |
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2021-05-25 14:45 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-05-25 15:22 |
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Articles in Press |
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2021-05-25 15:22 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-06-15 06:41 |
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Typeset the Manuscript |
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2021-07-08 11:33 |
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Publish the Manuscript Online |
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2021-07-10 10:08 |
ISSN |
1948-5204 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Biochemistry & Molecular Biology |
Manuscript Type |
Review |
Article Title |
Systems-level biomarkers identification and drug repositioning in colorectal cancer
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Manuscript Source |
Invited Manuscript |
All Author List |
Hande Beklen, Esra Yildirim, Medi Kori, Beste Turanli and Kazim Yalcin Arga |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
TUBITAK (Hande Beklen and Kazim Yalcin Arga) |
119S174 |
Marmara University Research Fund (BAPKO) |
FEN-C-YLP-120619-0199 |
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Corresponding Author |
Kazim Yalcin Arga, PhD, Professor, Department of Bioengineering, Marmara University, Goztepe, Istanbul 34722, Türkiye. kazim.arga@marmara.edu.tr |
Key Words |
Colorectal cancer; Colon cancer; Systems biology; Biomarker; Drug repositioning; Omics |
Core Tip |
Colorectal cancer (CRC) is the most commonly diagnosed cancer in women and men worldwide. Due to the lack of clinical symptoms, it is difficult for CRC patients to diagnose it in the early stages. There is an urgent need for alternative, inexpensive and easy-to-measure methods for screening and therapy. Systems biology and drug repositioning (DR) approaches are being used to discover biomarkers and novel targets as well as, existing drugs with different indications to develop new therapeutics and treatment strategies. Our goal was to provide an overview of systems-level biomarkers and insights into DR strategies for the treatment of CRC. |
Publish Date |
2021-07-10 10:08 |
Citation |
Beklen H, Yildirim E, Kori M, Turanli B, Arga KY. Systems-level biomarkers identification and drug repositioning in colorectal cancer. World J Gastrointest Oncol 2021; 13(7): 638-661 |
URL |
https://www.wjgnet.com/1948-5204/full/v13/i7/638.htm |
DOI |
https://dx.doi.org/10.4251/wjgo.v13.i7.638 |
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