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10/12/2021 6:53:35 AM | Browse: 479 | Download: 931
Publication Name World Journal of Gastroenterology
Manuscript ID 65546
Country/Territory Italy
Received
2021-03-09 16:30
Peer-Review Started
2021-03-09 16:34
To Make the First Decision
Return for Revision
2021-05-01 16:33
Revised
2021-05-17 14:17
Second Decision
2021-08-25 03:16
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-08-25 07:44
Articles in Press
2021-08-25 07:44
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-09-07 03:24
Typeset the Manuscript
2021-10-09 03:16
Publish the Manuscript Online
2021-10-12 06:53
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Fecal metabolomics' profile: A comparative study from colorectal cancer vs adenomatous polyps’ patients
Manuscript Source Invited Manuscript
All Author List Giulia Nannini, Gaia Meoni, Leonardo Tenori, Maria Novella Ringressi, Antonio Taddei, Elena Niccolai, Simone Baldi, Edda Russo, Claudio Luchinat and Amedeo Amedei
ORCID
Author(s) ORCID Number
Giulia Nannini http://orcid.org/0000-0002-6481-6864
Gaia Meoni http://orcid.org/0000-0002-8608-4641
Leonardo Tenori http://orcid.org/0000-0001-6438-059X
Maria Novella Ringressi http://orcid.org/0000-0002-1644-0583
Antonio Taddei http://orcid.org/0000-0003-2963-4085
Elena Niccolai http://orcid.org/0000-0002-9205-8079
Simone Baldi http://orcid.org/0000-0002-5151-2618
Edda Russo http://orcid.org/0000-0003-3141-1091
Claudio Luchinat http://orcid.org/0000-0003-2271-8921
Amedeo Amedei http://orcid.org/0000-0002-6797-9343
Funding Agency and Grant Number
Corresponding Author Amedeo Amedei, BSc, Reader (Associate Professor), Department of Clinical and Experimental Medicine, University of Florence, Largo Brambilla 3, Florence 50134, Italy. aamedei@unifi.it
Key Words Colorectal cancer; Adenomatous polyps; Nuclear magnetic resonance metabolomics; Fecal samples; Fecal metabolomics
Core Tip The third most common cause of death in both men and women worldwide is colorectal cancer (CRC). Fecal occult blood and serum tumor related markers are the indicators currently used in the clinic, but the lack of sensitivity and precision of these markers limits their use in the CRC diagnosis. The colonoscopy is the gold-standard screening technique for CRC, but it is a costly and extremely invasive procedure. The use of readily accessible biological samples, such as stool specimens, in conjunction with high-throughput molecular profiling techniques, could significantly contribute to the diagnosis and understanding of the patient relationship with CRC. Based on these assumptions we have compared with healthy subjects the fecal NMR metabolomic profiles of patients with colorectal cancer or adenomatous polyposis.
Publish Date 2021-10-12 06:53
Citation Nannini G, Meoni G, Tenori L, Ringressi MN, Taddei A, Niccolai E, Baldi S, Russo E, Luchinat C, Amedei A. Fecal metabolomics' profile: A comparative study from colorectal cancer vs adenomatous polyps’ patients. World J Gastroenterol 2021; 27(38): 6430-6441
URL https://www.wjgnet.com/1007-9327/full/v27/i38/6430.htm
DOI https://dx.doi.org/10.3748/wjg.v27.i38.6430
Full Article (PDF) WJG-27-6430.pdf
Full Article (Word) WJG-27-6430.docx
Manuscript File 65546-Review-FilipodiaCL.docx
Answering Reviewers 65546-Answering reviewers.pdf
Audio Core Tip 65546-Audio core tip.m4a
Biostatistics Review Certificate 65546-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 65546-Conflict-of-interest statement.pdf
Copyright License Agreement 65546-Copyright license agreement.pdf
Institutional Review Board Approval Form or Document 65546-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 65546-Language certificate.pdf
Supplementary Material 65546-Supplementary material.pdf
Peer-review Report 65546-Peer-review(s).pdf
Scientific Misconduct Check 65546-Bing-Wu YXJ-2.jpg
Scientific Misconduct Check 65546-Bing-Ma YJ-1.jpg
Scientific Misconduct Check 65546-Scientific misconduct check.pdf
Scientific Editor Work List 65546-Scientific editor work list.pdf