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Articles Published Processes
9/18/2021 9:35:02 AM | Browse: 644 | Download: 728
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Received |
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2021-03-12 14:02 |
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Peer-Review Started |
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2021-03-12 14:09 |
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To Make the First Decision |
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Return for Revision |
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2021-05-05 14:39 |
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Revised |
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2021-05-13 06:34 |
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Second Decision |
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2021-08-18 03:20 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-08-18 08:09 |
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Articles in Press |
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2021-08-18 08:09 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2021-09-17 02:54 |
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Publish the Manuscript Online |
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2021-09-18 09:35 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Minireviews |
| Article Title |
Lipid droplets as metabolic determinants for stemness and chemoresistance in cancer
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Alba Royo-Garcia, Sarah Courtois, Beatriz Parejo-Alonso, Pilar Espiau-Romera and Patricia Sancho |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Miguel Servet Fellowship |
CP16/00121 |
| FIS (Fondo Investigaciones Sanitarias) grants |
PI17/00082 |
| FIS (Fondo Investigaciones Sanitarias) grants |
PI20/00942 |
| the Worldwide Cancer Research Charity together with Fundación Científica Asociación Española contra el Cáncer (FCAECC) |
19-0250 |
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| Corresponding Author |
Patricia Sancho, PhD, Senior Researcher, Hospital Universitario Miguel Servet, IIS Aragon, Isabel la Catolica 1-3, Zaragoza 50009, Spain. psancho@iisaragon.es |
| Key Words |
Lipids; Lipid droplets; Lipid metabolism; Stemness; Cancer stem cells; Chemoresistance |
| Core Tip |
Increasing evidence suggests that lipid droplets (LDs) support cancer stem cells (CSCs) functionality at different levels. Indeed, an increased LD content has been linked to tumorigenicity, metastatic spread and chemoresistance in different cancer types, highlighting their value as prognostic and treatment response predictive biomarker. A deeper understanding of the molecular mechanisms by which LDs control these processes would expedite the discovery of novel potentially druggable targets and the design of more efficient therapeutic strategies aimed at eliminating highly tumorigenic CSCs. |
| Publish Date |
2021-09-18 09:35 |
| Citation |
Royo-García A, Courtois S, Parejo-Alonso B, Espiau-Romera P, Sancho P. Lipid droplets as metabolic determinants for stemness and chemoresistance in cancer. World J Stem Cells 2021; 13(9): 1307-1317 |
| URL |
https://www.wjgnet.com/1948-0210/full/v13/i9/1307.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v13.i9.1307 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
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