Publication Name	World Journal of Clinical Oncology
Manuscript ID	65669
Country	United States

Received	2021-03-12 14:18
Peer-Review Started	2021-03-12 14:36
To Make the First Decision
Return for Revision	2021-04-06 03:31
Revised	2021-04-19 19:59
Second Decision	2021-04-28 07:51
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2021-04-28 08:20
Articles in Press	2021-04-28 08:20
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-05-10 09:52
Publish the Manuscript Online	2021-05-22 10:39

ISSN	2218-4333 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Review
Article Title	Cellular based treatment modalities for unresectable hepatocellular carcinoma
Manuscript Source	Invited Manuscript
All Author List	Konstantinos Damiris, Hamza Abbad and Nikolaos Pyrsopoulos
ORCID	Author(s) ORCID Number Konstantinos Damiris http://orcid.org/0000-0001-9972-740X Hamza Abbad http://orcid.org/0000-0002-0655-9564 Nikolaos Pyrsopoulos http://orcid.org/0000-0002-6950-8174
Funding Agency and Grant Number
Corresponding Author	Nikolaos Pyrsopoulos, FAASLD, AGAF, FACG, MD, PhD, Professor, Department of Medicine, Division of Gastroenterology and Hepatology, Rutgers New Jersey Medical School, 185 South Orange Ave, Newark, NJ 07103, United States. pyrsopni@njms.rutgers.edu
Key Words	Hepatocellular carcinoma; Immunotherapy; Immune cells; Adoptive T cell therapy; Chimeric antigen receptor-T cell; Clinical trials
Core Tip	Over the recent years investigation for safe and effective treatments for unresectable hepatocellular carcinoma (HCC) has shifted focus from various chemotherapeutic agents to immune based therapy. Although far from being finalized, immune cell-based therapy has shown efficacy in a variety of clinical trials, indicating possible future utilization alone or in combination for the prevention and treatment of HCC.
Publish Date	2021-05-22 10:39
Citation	Damiris K, Abbad H, Pyrsopoulos N. Cellular based treatment modalities for unresectable hepatocellular carcinoma. World J Clin Oncol 2021; 12(5): 290-308
URL	https://www.wjgnet.com/2218-4333/full/v12/i5/290.htm
DOI	https://dx.doi.org/10.5306/wjco.v12.i5.290

Full Article (PDF)	WJCO-12-290.pdf
Full Article (Word)	WJCO-12-290.docx
Manuscript File	65669_Auto_Edited-ZMG.docx
Answering Reviewers	65669-Answering reviewers.pdf
Audio Core Tip	65669-Audio core tip.m4a
Conflict-of-Interest Disclosure Form	65669-Conflict-of-interest statement.pdf
Copyright License Agreement	65669-Copyright license agreement.pdf
Peer-review Report	65669-Peer-review(s).pdf
Scientific Misconduct Check	65669-Scientific misconduct check.pdf
Scientific Editor Work List	65669-Scientific editor work list.pdf