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Articles Published Processes
10/20/2021 7:18:39 AM | Browse: 550 | Download: 1320
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Received |
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2021-03-16 17:58 |
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Peer-Review Started |
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2021-03-16 18:06 |
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To Make the First Decision |
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Return for Revision |
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2021-05-01 04:47 |
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Revised |
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2021-05-10 22:10 |
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Second Decision |
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2021-09-03 03:06 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-09-03 06:58 |
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Articles in Press |
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2021-09-03 06:58 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-09-14 00:51 |
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Typeset the Manuscript |
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2021-10-18 05:53 |
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Publish the Manuscript Online |
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2021-10-20 07:18 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Editorial |
| Article Title |
Importance of BRCA mutation in the current treatment of pancreatic cancer beyond maintenance
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Joaquina Martínez-Galán, Isabel Rodriguez and Octavio Caba |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Junta de Andalucía |
PC-0498-2017 |
| Junta de Andalucía |
PC-0549-2017 |
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| Corresponding Author |
Octavio Caba, PhD, Professor, Institute of Biopathology and Regenerative Medicine (IBIMER), University of Granada, Avenida del Conocimiento s/n, Granada 18016, Spain. ocaba@ugr.es |
| Key Words |
Pancreatic cancer; Treatment; BRCA; Mutation; Poly(ADP-ribose) polymerase inhibitor; Maintenance |
| Core Tip |
Pancreatic cancer remains one of the most lethal malignant neoplasms, and available treatments have several limitations. Genetic studies are not currently recommended to support treatment selection. However, BRCA gene mutation has been associated with superior survival outcomes in patients treated with platinum-based chemotherapy. Hence, it appears appropriate to consider the BRCA gene status of patients with this cancer among clinical criteria for the selection of first-line chemotherapy regimen. |
| Publish Date |
2021-10-20 07:18 |
| Citation |
Martínez-Galán J, Rodriguez I, Caba O. Importance of BRCA mutation in the current treatment of pancreatic cancer beyond maintenance. World J Gastroenterol 2021; 27(39): 6515-6521 |
| URL |
https://www.wjgnet.com/1007-9327/full/v27/i39/6515.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v27.i39.6515 |
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