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1/12/2022 4:01:56 AM | Browse: 225 | Download: 355
Publication Name World Journal of Clinical Cases
Manuscript ID 65729
Country Taiwan
Received
2021-03-24 12:28
Peer-Review Started
2021-03-24 12:30
To Make the First Decision
Return for Revision
2021-10-16 21:49
Revised
2021-11-04 08:41
Second Decision
2021-12-06 03:22
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-12-08 05:18
Articles in Press
2021-12-08 05:18
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-11-28 13:52
Typeset the Manuscript
2021-12-31 05:37
Publish the Manuscript Online
2022-01-12 04:01
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Critical Care Medicine
Manuscript Type Case Report
Article Title Successful management of delirium with dexmedetomidine in a patient with haloperidol-induced neuroleptic malignant syndrome: A case report
Manuscript Source Unsolicited Manuscript
All Author List Chi-Ju Yang, Ching-Tang Chiu, Yu-Chang Yeh and Anne Chao
ORCID
Author(s) ORCID Number
Chi-Ju Yang http://orcid.org/0000-0002-4230-8973
Ching-Tang Chiu http://orcid.org/0000-0002-6135-8378
Yu-Chang Yeh http://orcid.org/0000-0001-5143-5520
Anne Chao http://orcid.org/0000-0002-7170-3817
Funding Agency and Grant Number
Funding Agency Grant Number
National Taiwan University Hospital Fund MS 213
Corresponding Author Anne Chao, MD, Doctor, Department of Anesthesiology, National Taiwan University Hospital, No. 7 Chung Shan South Road, Taipei 100220, Taiwan. chaoanne123@gmail.com
Key Words Haloperidol; Dexmedetomidine; Delirium; Neuroleptic malignant syndrome; Alpha-2 adrenergic agonists; Case report
Core Tip Neuroleptic malignant syndrome (NMS), a life-threatening condition characterized by hyperthermia, rigidity, altered mental status, and dysautonomia, can occur in 0.02%–3% of patients who receive haloperidol. Herein, we report a case of lorazepam-induced agitated delirium treated with haloperidol, which further triggered NMS. The NMS was effectively managed with medical therapy and dexmedetomidine, a versatile and highly selective short-acting alpha-2 adrenergic agonist with sedative-hypnotic and anxiolytic effects. Dexmedetomidine may be clinically helpful for the management of NMS because of its sympatholytic activity. In the presence of rapid shallow breathing, dexmedetomidine may provide better patient comfort with less respiratory depression than does propofol.
Publish Date 2022-01-12 04:01
Citation Yang CJ, Chiu CT, Yeh YC, Chao A. Successful management of delirium with dexmedetomidine in a patient with haloperidol-induced neuroleptic malignant syndrome: A case report. World J Clin Cases 2022; 10(2): 625-630
URL https://www.wjgnet.com/2307-8960/full/v10/i2/625.htm
DOI https://dx.doi.org/10.12998/wjcc.v10.i2.625
Full Article (PDF) WJCC-10-625.pdf
Full Article (Word) WJCC-10-625.docx
Manuscript File 65729_Auto_Edited.docx
Answering Reviewers 65729-Answering reviewers.pdf
Audio Core Tip 65729-Audio core tip.aac
Conflict-of-Interest Disclosure Form 65729-Conflict-of-interest statement.pdf
Copyright License Agreement 65729-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 65729-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 65729-Informed consent statement.pdf
Peer-review Report 65729-Peer-review(s).pdf
Scientific Misconduct Check 65729-CrossCheck.png
Scientific Editor Work List 65729_BPG_Scientific_editor_work_list.pdf