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Articles Published Processes
1/12/2022 4:01:56 AM | Browse: 341 | Download: 746
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Received |
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2021-03-24 12:28 |
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Peer-Review Started |
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2021-03-24 12:30 |
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To Make the First Decision |
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Return for Revision |
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2021-10-16 21:49 |
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Revised |
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2021-11-04 08:41 |
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Second Decision |
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2021-12-06 03:22 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-12-08 05:18 |
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Articles in Press |
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2021-12-08 05:18 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-11-28 13:52 |
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Typeset the Manuscript |
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2021-12-31 05:37 |
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Publish the Manuscript Online |
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2022-01-12 04:01 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Critical Care Medicine |
| Manuscript Type |
Case Report |
| Article Title |
Successful management of delirium with dexmedetomidine in a patient with haloperidol-induced neuroleptic malignant syndrome: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Chi-Ju Yang, Ching-Tang Chiu, Yu-Chang Yeh and Anne Chao |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Taiwan University Hospital Fund |
MS 213 |
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| Corresponding Author |
Anne Chao, MD, Doctor, Doctor, Department of Anesthesiology, National Taiwan University Hospital, No. 7 Chung Shan South Road, Taipei 100220, Taiwan. chaoanne123@gmail.com |
| Key Words |
Haloperidol; Dexmedetomidine; Delirium; Neuroleptic malignant syndrome; Alpha-2 adrenergic agonists; Case report |
| Core Tip |
Neuroleptic malignant syndrome (NMS), a life-threatening condition characterized by hyperthermia, rigidity, altered mental status, and dysautonomia, can occur in 0.02%–3% of patients who receive haloperidol. Herein, we report a case of lorazepam-induced agitated delirium treated with haloperidol, which further triggered NMS. The NMS was effectively managed with medical therapy and dexmedetomidine, a versatile and highly selective short-acting alpha-2 adrenergic agonist with sedative-hypnotic and anxiolytic effects. Dexmedetomidine may be clinically helpful for the management of NMS because of its sympatholytic activity. In the presence of rapid shallow breathing, dexmedetomidine may provide better patient comfort with less respiratory depression than does propofol. |
| Publish Date |
2022-01-12 04:01 |
| Citation |
Yang CJ, Chiu CT, Yeh YC, Chao A. Successful management of delirium with dexmedetomidine in a patient with haloperidol-induced neuroleptic malignant syndrome: A case report. World J Clin Cases 2022; 10(2): 625-630 |
| URL |
https://www.wjgnet.com/2307-8960/full/v10/i2/625.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v10.i2.625 |
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