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9/22/2021 8:09:41 AM | Browse: 419 | Download: 616
Publication Name World Journal of Hepatology
Manuscript ID 65732
Country Brazil
Received
2021-03-14 16:17
Peer-Review Started
2021-03-14 17:11
To Make the First Decision
Return for Revision
2021-04-06 16:12
Revised
2021-04-21 00:03
Second Decision
2021-07-26 03:25
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-07-26 07:53
Articles in Press
2021-07-26 07:53
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-08-12 00:55
Typeset the Manuscript
2021-09-15 02:39
Publish the Manuscript Online
2021-09-22 08:09
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Minireviews
Article Title Hepatocellular carcinoma in non-alcoholic fatty liver disease: A growing challenge
Manuscript Source Invited Manuscript
All Author List Ângelo Z Mattos, Jose D Debes, Renu Dhanasekaran, Jihane N Benhammou, Marco Arrese, André Luiz V Patrício, Amanda C Zilio and Angelo A Mattos
ORCID
Author(s) ORCID Number
Ângelo Z Mattos http://orcid.org/0000-0002-3063-0199
Jose D Debes http://orcid.org/0000-0002-1512-2604
Renu Dhanasekaran http://orcid.org/0000-0001-8819-7511
Jihane N Benhammou http://orcid.org/0000-0003-2442-5145
Marco Arrese http://orcid.org/0000-0002-0499-4191
André Luiz V Patrício http://orcid.org/0000-0002-2622-9802
Amanda C Zilio http://orcid.org/0000-0002-5657-1895
Angelo A Mattos http://orcid.org/0000-0003-2417-9765
Funding Agency and Grant Number
Funding Agency Grant Number
EU Horizon 2020 825510
Robert Wood Johnson Foundation, Harold Amos Medical Faculty Development Program (to Debes JD)
Fondo Nacional de Ciencia y Tecnología de Chile (FONDECYT) to MA 1191145
Corresponding Author Ângelo Z Mattos, MD, MSc, Professor, Graduate Program in Medicine: Hepatology, Federal University of Health Sciences of Porto Alegre, 154, Professor Annes Dias St., office 1103, Porto Alegre 90020-090, Rio Grande do Sul, Brazil. angmattos@hotmail.com
Key Words Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis; Hepatocellular carcinoma; Hepatocarcinogenesis; Surveillance
Core Tip Non-alcoholic fatty liver disease (NAFLD) is a growing cause of hepatocellular carcinoma (HCC), and liver cancer is one of the leading causes of cancer-related death worldwide. There are particular genetic and immune-mediated mechanisms for hepatocarcinogenesis in NAFLD. Moreover, HCC can develop in NAFLD in the absence of cirrhosis. Finally, the characteristics of NAFLD and its high prevalence lead to important challenges regarding surveillance for liver cancer in this population. This review will approach the most important issues concerning NAFLD-related HCC.
Publish Date 2021-09-22 08:09
Citation Mattos ÂZ, Debes JD, Dhanasekaran R, Benhammou JN, Arrese M, Patrício ALV, Zilio AC, Mattos AA. Hepatocellular carcinoma in non-alcoholic fatty liver disease: A growing challenge. World J Hepatol 2021; 13(9): 1107-1121
URL https://www.wjgnet.com/1948-5182/full/v13/i9/1107.htm
DOI https://dx.doi.org/10.4254/wjh.v13.i9.1107
Full Article (PDF) WJH-13-1107.pdf
Full Article (Word) WJH-13-1107.docx
Manuscript File 65732-Review-Filipodia-CL.docx
Answering Reviewers 65732-Answering reviewers.pdf
Audio Core Tip 65732-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 65732-Conflict-of-interest statement.pdf
Copyright License Agreement 65732-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 65732-Grant application form(s).pdf
Non-Native Speakers of English Editing Certificate 65732-Language certificate.pdf
Peer-review Report 65732-Peer-review(s).pdf
Scientific Misconduct Check 65732-Bing-Liu M-1.png
Scientific Misconduct Check 65732-Bing-Liu M-2.png
Scientific Misconduct Check 65732-Scientific misconduct check.pdf
Scientific Editor Work List 65732-Scientific editor work list.pdf