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Articles Published Processes
9/22/2021 8:09:41 AM | Browse: 561 | Download: 994
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Received |
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2021-03-14 16:17 |
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Peer-Review Started |
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2021-03-14 17:11 |
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To Make the First Decision |
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Return for Revision |
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2021-04-06 16:12 |
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Revised |
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2021-04-21 00:03 |
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Second Decision |
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2021-07-26 03:25 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-07-26 07:53 |
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Articles in Press |
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2021-07-26 07:53 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-08-12 00:55 |
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Typeset the Manuscript |
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2021-09-15 02:39 |
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Publish the Manuscript Online |
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2021-09-22 08:09 |
ISSN |
1948-5182 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Minireviews |
Article Title |
Hepatocellular carcinoma in non-alcoholic fatty liver disease: A growing challenge
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Manuscript Source |
Invited Manuscript |
All Author List |
Ângelo Z Mattos, Jose D Debes, Renu Dhanasekaran, Jihane N Benhammou, Marco Arrese, André Luiz V Patrício, Amanda C Zilio and Angelo A Mattos |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
EU Horizon 2020 |
825510 |
Robert Wood Johnson Foundation, Harold Amos Medical Faculty Development Program (to Debes JD) |
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Fondo Nacional de Ciencia y Tecnología de Chile (FONDECYT) to MA |
1191145 |
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Corresponding Author |
Ângelo Z Mattos, MD, MSc, Professor, Graduate Program in Medicine: Hepatology, Federal University of Health Sciences of Porto Alegre, 154, Professor Annes Dias St., office 1103, Porto Alegre 90020-090, Rio Grande do Sul, Brazil. angmattos@hotmail.com |
Key Words |
Non-alcoholic fatty liver disease; Non-alcoholic steatohepatitis; Hepatocellular carcinoma; Hepatocarcinogenesis; Surveillance |
Core Tip |
Non-alcoholic fatty liver disease (NAFLD) is a growing cause of hepatocellular carcinoma (HCC), and liver cancer is one of the leading causes of cancer-related death worldwide. There are particular genetic and immune-mediated mechanisms for hepatocarcinogenesis in NAFLD. Moreover, HCC can develop in NAFLD in the absence of cirrhosis. Finally, the characteristics of NAFLD and its high prevalence lead to important challenges regarding surveillance for liver cancer in this population. This review will approach the most important issues concerning NAFLD-related HCC. |
Publish Date |
2021-09-22 08:09 |
Citation |
Mattos ÂZ, Debes JD, Dhanasekaran R, Benhammou JN, Arrese M, Patrício ALV, Zilio AC, Mattos AA. Hepatocellular carcinoma in non-alcoholic fatty liver disease: A growing challenge. World J Hepatol 2021; 13(9): 1107-1121 |
URL |
https://www.wjgnet.com/1948-5182/full/v13/i9/1107.htm |
DOI |
https://dx.doi.org/10.4254/wjh.v13.i9.1107 |
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