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Articles Published Processes
12/15/2021 9:38:23 AM | Browse: 491 | Download: 1117
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Received |
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2021-03-16 20:18 |
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Peer-Review Started |
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2021-03-16 20:53 |
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To Make the First Decision |
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Return for Revision |
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2021-05-05 02:03 |
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Revised |
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2021-05-25 12:17 |
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Second Decision |
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2021-09-14 03:39 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-09-17 02:53 |
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Articles in Press |
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2021-09-17 02:53 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-11-06 04:40 |
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Typeset the Manuscript |
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2021-12-03 12:26 |
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Publish the Manuscript Online |
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2021-12-15 09:38 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychiatry |
| Manuscript Type |
Case Control Study |
| Article Title |
BDNF methylation and mRNA expression in brain and blood of completed suicides in Slovenia
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Sandra Ropret, Katarina Kouter, Tomaž Zupanc and Alja Videtic Paska |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Slovenian Research Agency |
P1-0390 |
| Slovenian Research Agency |
J3-7132 |
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| Corresponding Author |
Alja Videtic Paska, PhD, Associate Professor, Institute of Biochemistry and Molecular Genetics, Faculty of Medicine, University of Ljubljana, Vrazov trg 2, Ljubljana SI-1000, Slovenia. alja.videtic@mf.uni-lj.si |
| Key Words |
Suicidal behavior; Epigenetics; Next-generation sequencing; Brain; Blood; Caucasian |
| Core Tip |
BDNF methylation analysis of brain tissues did not show differences between control subjects and suicide victims, although there was higher expression of BDNF transcript I-IX in Brodmann area 9 of the suicide victims. Furthermore, the data obtained from blood are interesting, especially in terms of the direction of the effects, although due to the extensively degraded blood RNA, we were not able to confirm these effects on mRNA expression. Although suicide is a multifactorial disorder, our data overall further support the previously implicated role of BDNF in suicidality. |
| Publish Date |
2021-12-15 09:38 |
| Citation |
Ropret S, Kouter K, Zupanc T, Videtic Paska A. BDNF methylation and mRNA expression in brain and blood of completed suicides in Slovenia. World J Psychiatr 2021; 11(12): 1301-1313 |
| URL |
https://www.wjgnet.com/2220-3206/full/v11/i12/1301.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v11.i12.1301 |
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