Publication Name	World Journal of Gastroenterology
Manuscript ID	65799
Country	Japan

Received	2021-03-23 05:36
Peer-Review Started	2021-03-16 07:11
To Make the First Decision
Return for Revision	2021-04-29 22:07
Revised	2021-05-13 06:40
Second Decision	2021-09-02 02:54
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2021-09-02 07:10
Articles in Press	2021-09-02 07:10
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2021-09-27 01:49
Publish the Manuscript Online	2021-09-29 11:12

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Impact of Helicobacter pylori infection on gut microbiota
Manuscript Source	Invited Manuscript
All Author List	Chikara Iino and Tadashi Shimoyama
ORCID	Author(s) ORCID Number Chikara Iino http://orcid.org/0000-0001-6844-4415 Tadashi Shimoyama http://orcid.org/0000-0001-9615-0000
Funding Agency and Grant Number
Corresponding Author	Tadashi Shimoyama, FACG, MD, PhD, Director, Director, Department of Internal Medicine, Aomori General Health Examination Center, 2-19-12 Tsukuda, Aomori 030-0962, Japan. tsimo@hirosaki-u.ac.jp
Key Words	Helicobacter pylori; Gut microbiota; Atrophic gastritis; Eradication; Proton pump inhibitor
Core Tip	Helicobacter pylori (H. pylori) eradication alters gut microbiota within a short period after eradication; this is attributed to antibiotics and proton pump inhibitors. However, most of these alterations reverse back to baseline levels over a long period of time. Modification of acidity in the stomach with mucosal atrophy caused by H. pylori infection alters the gut microbiota. As the human gut microbiome is diverse among individuals, a large population size is needed to study. Adjustment of biases associated with the composition of the gut microbiota is also crucial for accurate evaluation of the association between H. pylori infection and the gut microbiota.
Publish Date	2021-09-29 11:12
Citation	Iino C, Shimoyama T. Impact of Helicobacter pylori infection on gut microbiota. World J Gastroenterol 2021; 27(37): 6224-6230
URL	https://www.wjgnet.com/1007-9327/full/v27/i37/6224.htm
DOI	https://dx.doi.org/10.3748/wjg.v27.i37.6224

Full Article (PDF)	WJG-27-6224.pdf
Full Article (Word)	WJG-27-6224.docx
Manuscript File	65799_Auto_Edited-JPY.docx
Answering Reviewers	65799-Answering reviewers.pdf
Audio Core Tip	65799-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	65799-Conflict-of-interest statement.pdf
Copyright License Agreement	65799-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	65799-Language certificate.pdf
Peer-review Report	65799-Peer-review(s).pdf
Scientific Misconduct Check	65799-Scientific misconduct check.pdf
Scientific Editor Work List	65799-Scientific editor work list.pdf
CrossCheck Report	65799-CrossCheck report.pdf