| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Gossip in the gut: Quorum sensing, a new player in the host-microbiota interactions
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Garance Coquant, Doriane Aguanno, Sandrine Pham, Nathan Grellier, Sophie Thenet, Véronique Carrière, Jean-Pierre Grill and Philippe Seksik |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Fondation pour la Recherche Médicale |
EQU202003010171 |
| Association François Aupetit |
AHLs 2019 |
| Association François Aupetit |
AHLs 2021 |
| Fondation pour la Recherche Médical FRM |
ECO201806006843 |
| CORDDIM, Ile-de-France Region |
|
|
| Corresponding Author |
Philippe Seksik, MD, PhD, Professor, Department of Gastroenterology and Nutrition, Saint-Antoine Hospital, APHP, 184, rue du Faubourg Saint-Antoine, Paris 75012, France. philippe.seksik@aphp.fr |
| Key Words |
Inflammatory bowel disease; Quorum sensing; Gut microbiota; Dysbiosis; Inflammation; Intestinal barrier |
| Core Tip |
Host-microbiota interactions play a crucial role in the pathophysiology of many intestinal diseases. While biological components have been repeatedly described, a largely overlooked component is quorum sensing (QS), a density-dependent system able to coordinate bacterial responses and interact with host cells constantly exposed to bacteria. This review intends to describe the different QS systems to show evidence that QS is part of the intestinal ecosystem and highlight its impact on intestinal epithelial barrier function, inflammation, and intestinal carcinogenesis. From this report, we open up a new area of intestinal physiology. |
| Publish Date |
2021-11-10 07:13 |
| Citation |
Coquant G, Aguanno D, Pham S, Grellier N, Thenet S, Carrière V, Grill JP, Seksik P. Gossip in the gut: Quorum sensing, a new player in the host-microbiota interactions. World J Gastroenterol 2021; 27(42): 7247-7270 |
| URL |
https://www.wjgnet.com/1007-9327/full/v27/i42/7247.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v27.i42.7247 |
