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        7/7/2021 8:39:46 AM | Browse: 610 | Download: 1617
    
    
        
        
    
        
            
                
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        2021-03-17 19:16 | 
    
    
        
            
                
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        2021-03-17 19:22 | 
    
    
        
            
                
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                    To Make the First Decision | 
                 
             
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        2021-04-06 17:11 | 
    
    
        
            
                
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                    Revised | 
                 
             
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        2021-04-20 08:56 | 
    
    
        
            
                
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        2021-06-03 06:08 | 
    
    
        
            
                
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                    Accepted by Journal Editor-in-Chief | 
                 
             
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                    Accepted by Executive Editor-in-Chief | 
                 
             
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        2021-06-03 11:56 | 
    
    
        
            
                
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                    Articles in Press | 
                 
             
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        2021-06-03 11:56 | 
    
    
        
            
                
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                    Publication Fee Transferred | 
                 
             
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                    Edit the Manuscript by Language Editor | 
                 
             
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        2021-06-10 23:34 | 
    
    
        
            
                
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                    Typeset the Manuscript | 
                 
             
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        2021-06-28 00:56 | 
    
            
                
                    
                        
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                            Publish the Manuscript Online | 
                         
                     
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                2021-07-07 08:39 | 
            
        
        
            
                | ISSN | 
                2307-8960 (online) | 
            
            
                | Open Access | 
                This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ | 
            
            
                | Copyright | 
                © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. | 
            
                    
                        | Article Reprints | 
                        
                            For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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                | Permissions | 
                
                    For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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                | Publisher | 
                Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA | 
            
            
                | Website | 
                http://www.wjgnet.com | 
            
        
    
        | Category | 
        Gastroenterology & Hepatology | 
    
    
        | Manuscript Type | 
        Minireviews | 
    
    
        | Article Title | 
        
                    Role of gastrointestinal system on transmission and pathogenesis of SARS-CoV-2
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        | Manuscript Source | 
        Invited Manuscript | 
    
    
        | All Author List | 
        Cem Simsek, Enes Erul and Hatice Yasemin Balaban | 
    
            
                | ORCID | 
                
                    
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        | Funding Agency and Grant Number | 
        
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        | Corresponding Author | 
        Cem Simsek, MD, Doctor, Doctor, Department of Gastroenterology, Hacettepe University Faculty of Medicine, Sihhiye, Ankara 06100, Türkiye. cemgsimsek@gmail.com | 
    
    
        | Key Words | 
        SARS-CoV-2; COVID-19; Gastrointestinal system; Transmission; Pathogenesis | 
    
    
        | Core Tip | 
        Angiotensin converting enzyme 2 is the target entry receptor for severe acute respiratory syndrome coronavirus 2 which is abundantly expressed in lung as well as in the gastric, duodenal, and rectal epithelium. This raises the question on potential transmission of the virus through gut via fecal-oral route. In addition to many studies showing viral RNA in faces, studies with animal models strengthen the evidence that the virus can be transmitted through the fecal-oral route. We underline the importance of raising awareness for the control of the pandemic by updating the information about the fecal-oral transmission route. | 
    
            
                | Publish Date | 
                2021-07-07 08:39 | 
            
    
        | Citation | 
        Simsek C, Erul E, Balaban HY. Role of gastrointestinal system on transmission and pathogenesis of SARS-CoV-2. World J Clin Cases 2021; 9(20): 5427-5434 | 
    
            
                | URL | 
                https://www.wjgnet.com/2307-8960/full/v9/i20/5427.htm | 
            
            
                | DOI | 
                https://dx.doi.org/10.12998/wjcc.v9.i20.5427 | 
            
    
    
        
                
        
     
 
                 
             
         
        
    
        
        
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