Publication Name	World Journal of Gastroenterology
Manuscript ID	6615
Country	Italy

Received	2013-10-25 14:35
Peer-Review Started	2013-10-25 19:37
To Make the First Decision	2013-12-26 11:17
Return for Revision	2013-12-26 21:12
Revised	2014-04-03 11:55
Second Decision	2014-06-26 16:54
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-06-26 17:35
Articles in Press	2014-06-26 17:58
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-10-17 09:28
Publish the Manuscript Online	2014-10-29 19:34

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	ADV36 adipogenic adenovirus in human liver disease
Manuscript Source	Invited Manuscript
All Author List	Francesca M Trovato, Daniela Catalano, Adriana Garozzo, G Fabio Martines, Clara Pirri and Guglielmo M Trovato
Funding Agency and Grant Number
Corresponding Author	Guglielmo M Trovato, MD, Department of Medical and Pediatric Sciences, Internal Medicine, University of Catania, Policlinico, Ed. 4, 4th floor, Via Santa Sofia, 95100 Catania, Italy. guglielmotrovato@unict.it
Key Words	Non-alcoholic fatty liver disease; Human adenovirus 36; obesity; Insulin resistance; Mediterranean diet; Ultrasound
Core Tip	There is evidence that environmental infections, and notably adipogenic adenoviruses ADV36 /ADV37 infections in humans, are associated with obesity, being causative contributing factors of obesity in humans and animals. Lifestyle-nutritional intervention, in patients with different ADV36 seropositive status, achieves different clinical outcomes, i.e., a greater effect, on bright liver, insulin resistance and obesity is observed in comparison with ADV36 seronegative patients. These effects are not dependent on a greater pre-interventional body weight and older age. Adipogenic adenovirus infections in humans are associated with obesity, but also with allied conditions, such as fatty liver, and can have different effects on the liver in humans and animals.
Publish Date	2014-10-29 19:34
Citation	Trovato FM, Catalano D, Garozzo A, Martines GF, Pirri C, Trovato GM. ADV36 adipogenic adenovirus in human liver disease. World J Gastroenterol 2014; 20(40): 14706-14716
URL	http://www.wjgnet.com/1007-9327/full/v20/i40/14706.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i40.14706

Full Article (PDF)	WJG-20-14706.pdf
Full Article (Word)	WJG-20-14706.doc
Manuscript File	6615-Review.docx
Answering Reviewers	6615-Answering reviewers.pdf
Copyright License Agreement	6615-Copyright assignment.pdf
Peer-review Report	6615-Peer review(s).pdf
Scientific Misconduct Check	6615-CrossCheck.jpg
Scientific Editor Work List	6615-Scientific editor work list.pdf