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9/10/2014 3:08:00 PM | Browse: 1326 | Download: 1114
Publication Name World Journal of Immunology
Manuscript ID 6618
Country United States
Received
2013-10-25 14:45
Peer-Review Started
2013-10-25 19:44
To Make the First Decision
2013-11-12 14:34
Return for Revision
2013-11-14 17:27
Revised
Second Decision
2014-01-20 08:54
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-01-20 10:03
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-03-25 17:57
Publish the Manuscript Online
2014-03-26 14:31
ISSN 2219-2824 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Immunology
Manuscript Type Minireviews
Article Title Role of myeloid-derived suppressor cells in autoimmune disease
Manuscript Source Invited Manuscript
All Author List Kristen R Crook and Peng Liu
Funding Agency and Grant Number
Corresponding Author Peng Liu, MD, PhD, Associate Professor, Department of Medicine, Thurston Arthritis Research Center, School of Medicine, University of North Carolina at Chapel Hill, 3300 Thurston Building, CB# 7280, 104 Manning Drive, Chapel Hill, NC 27599, United States. liupz@med.unc.edu
Key Words Myeloid-derived suppressor cells; Autoimmune disease; Autoimmunity; T cells; Chronic inflammation; Immune regulation
Core Tip Myeloid-derived suppressor cells (MDSCs) are a heterogeneous group of cells with immunosuppressive abilities. MDSCs inhibit T cell function and regulate immune responses in cancer and autoimmune diseases. Therapeutic administration of MDSCs in the mouse models of multiple sclerosis, rheumatoid arthritis, and diabetes has shown promising results. Thus, MDSCs have potential in cell-based treatments of autoimmune disorders. However, the role of MDSCs in autoimmunity is complex and not fully understood. Further studies are needed before new therapies can be implemented.
Publish Date 2014-03-26 14:31
Citation Crook KR, Liu P. Role of myeloid-derived suppressor cells in autoimmune disease. World J Immunol 2014; 4(1): 26-33 Available from: URL: http://www.wjgnet.com/2219-2824/full/v4/i1/26.htm DOI: http://dx.doi.org/10.5411/wji.v4.i1.26
URL http://www.wjgnet.com/2219-2824/full/v4/i1/26.htm
DOI http://dx.doi.org/10.5411/wji.v4.i1.26
Full Article (PDF) WJI-4-26.pdf
Full Article (Word) WJI-4-26.doc
Manuscript File 6618-Review.docx
Answering Reviewers 6618-Answering reviewers.pdf
Copyright License Agreement 6618-Copyright assignment.pdf
Peer-review Report 6618-Peer review(s).pdf
Scientific Editor Work List 6618-Scientific editor work list.doc