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Articles Published Processes
10/20/2021 7:18:39 AM | Browse: 452 | Download: 1406
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Received |
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2021-04-07 15:33 |
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Peer-Review Started |
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2021-04-07 15:37 |
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To Make the First Decision |
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Return for Revision |
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2021-05-27 19:51 |
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Revised |
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2021-07-07 10:58 |
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Second Decision |
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2021-09-02 02:54 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-09-02 07:55 |
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Articles in Press |
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2021-09-02 07:55 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-09-14 00:48 |
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Typeset the Manuscript |
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2021-10-18 01:01 |
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Publish the Manuscript Online |
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2021-10-20 07:18 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Observational Study |
| Article Title |
Diagnostic usefulness of selected proteases and acute phase factors in patients with colorectal adenocarcinoma
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Tadeusz Sebzda, Jan Gnus, Barbara Dziadkowiec, Miroslaw Latka and Jakub Gburek |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Barbara Dziadkowiec, MD, Doctor, Doctor, Department of Pathophysiology, Wroclaw Medical University, Marcinkowskiego 1, Wroclaw 50-368, Poland. dziadkowiecbarbara@gmail.com |
| Key Words |
Colorectal cancer; Cathepsin B; Acute phase reactansts; Colorectal adenocarcinoma; Acute phase factor |
| Core Tip |
We searched for biomarkers applicable to the early detection of colorectal adenocarcinoma. Five parameters were determined in sera of patients and healthy individuals: Cathepsin B activity, total sialic acids concentration, lipid-associated sialic acids concentration, elastase concentration, and alpha 1 antitrypsin activity. We performed receiver operating characteristic analysis for single and multiple parameters. While the sensitivity and specificity were not very high for single parameters, the combined analysis of cathepsin B, alpha 1 antitripsin, and total sialic acids concentration yielded 88% sensitivity and 100% specificity. We believe that this set of markers can be useful in clinical practice. |
| Publish Date |
2021-10-20 07:18 |
| Citation |
Sebzda T, Gnus J, Dziadkowiec B, Latka M, Gburek J. Diagnostic usefulness of selected proteases and acute phase factors in patients with colorectal adenocarcinoma. World J Gastroenterol 2021; 27(39): 6673-6688 |
| URL |
https://www.wjgnet.com/1007-9327/full/v27/i39/6673.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v27.i39.6673 |
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