Publication Name	World Journal of Gastroenterology
Manuscript ID	6656
Country	Ireland

Received	2013-10-26 12:27
Peer-Review Started	2013-10-27 12:25
To Make the First Decision	2013-11-13 13:34
Return for Revision	2013-11-14 13:27
Revised	2013-12-04 19:46
Second Decision	2014-01-20 17:09
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-01-20 18:12
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-05-06 13:32
Publish the Manuscript Online	2014-05-18 12:31

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Infectious Diseases
Manuscript Type	Topic Highlights
Article Title	Factors that mediate colonization of the human stomach by Helicobacter pylori
Manuscript Source	Invited Manuscript
All Author List	Ciara Dunne, Brendan Dolan and Marguerite Clyne
Funding Agency and Grant Number	Funding Agency Grant Number Irish Research Council for Science Engineering and Technology To Dunne C Health Research Board Ireland Science Foundation Ireland 08/SRC/B1393
Corresponding Author	Marguerite Clyne, PhD, School of Medicine and Medical Science and Conway Institute of Biomedical and Biomolecular Science, University College Dublin, Belfield, Dublin 4, Ireland. marguerite.clyne@ucd.ie
Key Words	Helicobacter pylori; Colonization; Infection; Gastric mucosa; Urease; Flagella; Polymorphisms; Adhesins; CagA; Type Ⅳ secretion system
Core Tip	Colonization of gastric mucus by Helicobacter pylori (H. pylori) key to the establishment of chronic infection. How H. pylori manages to colonise and survive in the hostile environment of the human stomach and avoid removal by “mucus flow” and killing by gastric acid is the subject of this review. We also discuss how bacterial and host factors may together go some way to explaining the susceptibility to colonization and the outcome of infection in different individuals. Understanding of how H. pylori causes chronic infection will likely serve as a valuable reference system for how other bacteria colonise mucosal surfaces.
Publish Date	2014-05-18 12:31
Citation	Dunne C, Dolan B, Clyne M. Factors that mediate colonization of the human stomach by Helicobacter pylori. World J Gastroenterol 2014; 20(19): 5610-5624
URL	http://www.wjgnet.com/1007-9327/full/v20/i19/5610.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i19.5610

Full Article (PDF)	WJG-20-5610.pdf
Full Article (Word)	WJG-20-5610.doc
Manuscript File	6656-Review.docx
Answering Reviewers	6656-Answering reviewers.pdf
Copyright License Agreement	6656-Copyright assignment.pdf
Peer-review Report	6656-Peer review(s).pdf
Scientific Editor Work List	6656-Scientific editor work list.doc