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10/21/2021 8:44:04 AM | Browse: 193 | Download: 255
Publication Name World Journal of Clinical Cases
Manuscript ID 66587
Country China
Received
2021-04-01 07:55
Peer-Review Started
2021-04-01 08:00
To Make the First Decision
Return for Revision
2021-04-28 03:21
Revised
2021-05-19 01:51
Second Decision
2021-07-02 12:50
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-07-02 13:34
Articles in Press
2021-07-02 13:34
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-09-13 11:24
Typeset the Manuscript
2021-10-18 00:56
Publish the Manuscript Online
2021-10-21 08:44
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Case Report
Article Title Hemophagocytic lymphohistiocytosis secondary to composite lymphoma: Two case reports
Manuscript Source Unsolicited Manuscript
All Author List Jing Shen, Jing-Shi Wang, Jian-Lan Xie, Lin Nong, Jia-Ning Chen and Zhao Wang
ORCID
Author(s) ORCID Number
Jing Shen http://orcid.org/0000-0002-0207-2185
Jing-Shi Wang http://orcid.org/0000-0001-5050-9225
Jian-Lan Xie http://orcid.org/0000-0001-9136-494X
Lin Nong http://orcid.org/0000-0002-1331-2420
Jia-Ning Chen http://orcid.org/0000-0003-4880-5986
Zhao Wang http://orcid.org/0000-0003-1067-4589
Funding Agency and Grant Number
Corresponding Author Zhao Wang, MD, Professor, Department of Hematology, Capital Medical University Affiliated Beijing Friendship Hospital, No. 95 Yongan Road, Xicheng District, Beijing 100000, China. wangzhao@ccmu.edu.cn
Key Words Hemophagocytosis; Hemophagocytic lymphohistiocytosis; Composite lymphoma; T-cell; B-cell; Case report
Core Tip Lymphoma-associated hemophagocytic lymphohistiocytosis (HLH) is a rare and life-threatening clinical disorder, especially composite lymphoma with mixed lineage features of T- and B-cell marker expressions is extremely rare. We report two cases of HLH secondary to bi-lineage composite lymphoma with the lymphocyte infiltrations both in the bone marrow and lymph nodes in adult patients. Case 1 patient showed typical features of combined B-cell and T-cell lymphoma in axillary lymph node and bone marrow biopsy. Case 2 patient showed typical features of T cell lymphoma in lymph node biopsy, and B cell lymphoma in bone marrow biopsy. Both of them highlight the diagnostic dilemma, therapeutic challenges and poor prognosis.
Publish Date 2021-10-21 08:44
Citation Shen J, Wang JS, Xie JL, Nong L, Chen JN, Wang Z. Hemophagocytic lymphohistiocytosis secondary to composite lymphoma: Two case reports. World J Clin Cases 2021; 9(30): 9159-9167
URL https://www.wjgnet.com/2307-8960/full/v9/i30/9159.htm
DOI https://dx.doi.org/10.12998/wjcc.v9.i30.9159
Full Article (PDF) WJCC-9-9159.pdf
Full Article (Word) WJCC-9-9159.docx
CARE Checklist–2016 66587-CARE-Checklist–2016-revision.pdf
Manuscript File 66587_Auto_Edited-ZMG-Webster J-Clear.docx
Answering Reviewers 66587-Answering reviewers.pdf
Audio Core Tip 66587-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 66587-Conflict-of-interest statement.pdf
Copyright License Agreement 66587-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 66587-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate 66587-Language certificate.pdf
Peer-review Report 66587-Peer-review(s).pdf
Scientific Misconduct Check 66587-Bing-Wang JL-1.jpg
Scientific Misconduct Check 66587-Scientific misconduct check.pdf
Scientific Editor Work List 66587-Scientific editor work list.pdf