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Articles Published Processes
7/26/2021 11:20:59 AM | Browse: 570 | Download: 1440
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Received |
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2021-03-31 10:51 |
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Peer-Review Started |
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2021-03-31 10:55 |
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To Make the First Decision |
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Return for Revision |
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2021-05-28 01:07 |
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Revised |
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2021-06-09 18:12 |
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Second Decision |
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2021-07-05 05:53 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-07-06 09:55 |
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Articles in Press |
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2021-07-06 09:55 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-07-15 00:08 |
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Typeset the Manuscript |
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2021-07-21 12:12 |
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Publish the Manuscript Online |
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2021-07-26 11:20 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Clinical Trials Study |
| Article Title |
Modified Xiaochaihu Decoction for gastroesophageal reflux disease: A randomized double-simulation controlled trial
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Zhe Li, Lin Tao, Sheng-Sheng Zhang, Xiao-Hong Sun, Su-Ning Chen and Jing Wu |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Beijing Municipal Science & Technology Commission |
Z141107002514176 |
| Capital Health Development Research Project |
2018-2-2231 |
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| Corresponding Author |
Sheng-Sheng Zhang, PhD, Chief Doctor, The Digestive Center, Beijing Hospital of Traditional Chinese Medicine Capital Medical University, No. 23 Art Gallery Back Street, Dongcheng District, Beijing 100010, China. zhangshengsheng@bjzhongyi.com |
| Key Words |
Gastroesophageal reflux disease; Traditional Chinese medicine; Esophageal sphincter pressure; Gastroesophageal reflux disease-Q scale score; Modified Xiaochaihu Decoction |
| Core Tip |
This multi-center, randomized, double-blind, double-simulation study, proved that Modified Xiaochaihu Decoction (MXD) has a similar therapeutic effect to omeprazole in the treatment of patients with typical symptoms of gastroesophageal reflux disease (GERD) and reflux esophagitis grades A and B. MXD was superior to omeprazole in improving lower esophageal sphincter resting pressure and reducing ineffective esophagus swallowing. The recurrence rate of symptoms was significantly lower than that of omeprazole within 1 and 3 mo after completing treatment. MXD may be an alternative treatment to proton pump inhibitor maintenance in patients with GERD. |
| Publish Date |
2021-07-26 11:20 |
| Citation |
Li Z, Tao L, Zhang SS, Sun XH, Chen SN, Wu J. Modified Xiaochaihu Decoction for gastroesophageal reflux disease: A randomized double-simulation controlled trial. World J Gastroenterol 2021; 27(28): 4710-4721 |
| URL |
https://www.wjgnet.com/1007-9327/full/v27/i28/4710.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v27.i28.4710 |
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