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Articles Published Processes
3/24/2022 2:13:21 PM | Browse: 457 | Download: 1551
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Received |
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2021-03-31 21:08 |
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Peer-Review Started |
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2021-03-31 21:28 |
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To Make the First Decision |
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Return for Revision |
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2021-07-27 02:22 |
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Revised |
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2021-08-01 07:34 |
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Second Decision |
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2022-02-21 07:28 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2022-02-23 21:03 |
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Articles in Press |
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2022-02-23 21:03 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-03-18 05:02 |
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Publish the Manuscript Online |
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2022-03-24 14:13 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Randomized Clinical Trial |
| Article Title |
Effect of a specific Escherichia coli Nissle 1917 strain on minimal/mild hepatic encephalopathy treatment
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Elina Manzhalii, Valentyna Moyseyenko, Vitalii Kondratiuk, Nataliia Molochek, Tetyana Falalyeyeva and Nazarii Kobyliak |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Nazarii Kobyliak, PhD, Associate Professor, Department of Endocrinology, Bogomolets National Medical University, Pushkinska 22a str, Kyiv 01601, Ukraine. nazariikobyliak@gmail.com |
| Key Words |
Hepatic encephalopathy; Chronic liver disease; cirrhosis; Gut microbiota; E. coli Nissle 1917; Cognitive functions; Stroop test; Rifaximin; Lactulose |
| Core Tip |
In a prospective, single-centre, open-label, randomized study, the short-term efficacy and safety of Escherichia coli Nissle (EcN) 1917 compared to that of lactulose and rifaximin in patients with hepatic encephalopathy were evaluated. The probiotic reduced the ammonia content and the level of serum proinflammatory cytokines, normalized the gut microbiota composition and improved the cognitive functions of patients with hepatic encephalopathy. The application of the EcN strain was more effective than lactulose treatment. |
| Publish Date |
2022-03-24 14:13 |
| Citation |
Manzhalii E, Moyseyenko V, Kondratiuk V, Molochek N, Falalyeyeva T, Kobyliak N. Effect of a specific Escherichia coli Nissle 1917 strain on minimal/mild hepatic encephalopathy treatment. World J Hepatol 2022; 14(3): 634-646 |
| URL |
https://www.wjgnet.com/1948-5182/full/v14/i3/634.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v14.i3.634 |
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