Publication Name	World Journal of Clinical Cases
Manuscript ID	66792
Country	China

Received	2021-04-08 14:27
Peer-Review Started	2021-04-08 14:30
To Make the First Decision
Return for Revision	2021-04-28 02:09
Revised	2021-05-09 09:46
Second Decision	2021-09-13 02:11
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2021-09-16 23:01
Articles in Press	2021-09-16 23:01
Publication Fee Transferred
Edit the Manuscript by Language Editor	2021-10-21 04:57
Typeset the Manuscript	2021-11-24 02:50
Publish the Manuscript Online	2021-11-30 09:35

ISSN	2307-8960 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Oncology
Manuscript Type	Retrospective Cohort Study
Article Title	Clinical features and survival of patients with multiple primary malignancies
Manuscript Source	Unsolicited Manuscript
All Author List	Xin-Kun Wang and Min-Hang Zhou
ORCID	Author(s) ORCID Number Xin-Kun Wang http://orcid.org/0000-0002-9574-9019 Min-Hang Zhou http://orcid.org/0000-0002-2094-4127
Funding Agency and Grant Number
Corresponding Author	Min-Hang Zhou, MM, Attending Doctor, Department of Geriatric Oncology, the Fourth Medical Center, Chinese PLA General Hospital, No. 51 Fucheng Road, Beijing 100048, China. zhou_minhang@163.com
Key Words	Multiple primary malignancies; Overall survival; Prognostic factor; Distant metastasis; Age
Core Tip	In the paper we investigated the clinical features and survival of 243 patients with multiple primary malignancies (MPM), including 222 patients with two malignancies and 21 patients with three malignancies. There was no survival difference between synchronous and metachronous MPM patients. After multivariate analyses, age > 65 years and distant metastasis were independent adverse prognostic factors for overall survival. In clinical procedure and follow-up of initial cancer, the occurrence of second or more cancer should be paid great attention to.
Publish Date	2021-11-30 09:35
Citation	Wang XK, Zhou MH. Clinical features and survival of patients with multiple primary malignancies. World J Clin Cases 2021; 9(34): 10484-10493
URL	https://www.wjgnet.com/2307-8960/full/v9/i34/10484.htm
DOI	https://dx.doi.org/10.12998/wjcc.v9.i34.10484

Full Article (PDF)	WJCC-9-10484.pdf
Full Article (Word)	WJCC-9-10484.docx
STROBE Statement	66792-STROBE-Statement-revision.docx
Manuscript File	66792-Review-Filipodia-CL.docx
Answering Reviewers	66792-Answering reviewers.pdf
Audio Core Tip	66792-Audio core tip.m4a
Biostatistics Review Certificate	66792-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form	66792-Conflict-of-interest statement.pdf
Copyright License Agreement	66792-Conflict-of-interest statement.pdf
Signed Informed Consent Form(s) or Document(s)	66792-Informed consent statement.pdf
Institutional Review Board Approval Form or Document	66792-Informed consent statement.pdf
Non-Native Speakers of English Editing Certificate	66792-Language certificate.pdf
Peer-review Report	66792-Peer-review(s).pdf
Scientific Misconduct Check	66792-Bing-Wang JL-1.jpg
Scientific Misconduct Check	66792-Bing Liu M-2.png
Scientific Editor Work List	66792-Scientific editor work list.pdf
CrossCheck Report	66792-CrossCheck report.pdf