BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
10/13/2021 8:37:10 AM | Browse: 706 | Download: 2262
 |
Received |
|
2021-04-14 20:08 |
|
Peer-Review Started |
|
2021-04-14 20:11 |
|
First Decision by Editorial Office Director |
|
2021-05-12 05:38 |
|
Return for Revision |
|
2021-05-12 05:38 |
|
Revised |
|
2021-06-07 22:26 |
 |
Publication Fee Transferred |
|
|
|
Second Decision by Editor |
|
2021-09-06 03:01 |
|
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2021-09-06 10:58 |
|
Articles in Press |
|
2021-09-06 10:58 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2021-09-26 00:54 |
|
Publish the Manuscript Online |
|
2021-10-13 08:37 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Basic Study |
| Article Title |
Metabolic and inflammatory functions of cannabinoid receptor type 1 are differentially modulated by adiponectin
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Qiong Wei, Jong Han Lee, Chia-Shan Wu, Qun S Zang, Shaodong Guo, Hui-Chen Lu and Yuxiang Sun |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| NIH |
DK118334 |
| NIH |
AG064869 |
| BrightFocus |
A2019630S |
|
| Corresponding Author |
Yuxiang Sun, MD, PhD, Associate Professor, Department of Nutrition, Texas A and M University, 214C Cater-Mattil; 2253 TAMU College Station, TX 77843-2253 Phone: 979-862-9143 (office); 979-862-9144 (lab). Fax: 979-458-3129, College Station TX, 7743, United States. yuxiangs@tamu.edu |
| Key Words |
Cannabinoid type 1 receptor; Adiponectin; Thermogenesis; Macrophages; Inflammation; Insulin resistance |
| Core Tip |
Antagonists of cannabinoid type 1 receptor (CB1) have been shown to promote body weight loss and improve insulin sensitivity. Cannabinoids have been shown to regulate adiponectin. However, it is unclear whether adiponectin is a key mediator of the functions of CB1. We compared metabolic and inflammatory phenotypes of CB1-null vs CB1/adiponectin double-knockout mice. Our findings reveal that CB1 functions through both adiponectin-dependent and adiponectin-independent mechanisms: CB1 regulates energy metabolism in an adiponectin-independent manner, and inflammation in an adiponectin-dependent manner. |
| Publish Date |
2021-10-13 08:37 |
| Citation |
Wei Q, Lee JH, Wu CS, Zang QS, Guo SD, Lu HC, Sun YX. Metabolic and inflammatory functions of cannabinoid receptor type 1 are differentially modulated by adiponectin. World J Diabetes 2021; 12(10): 1750-1764 |
| URL |
https://www.wjgnet.com/1948-9358/full/v12/i10/1750.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v12.i10.1750 |
All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.
