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Articles Published Processes
9/2/2014 10:31:00 AM | Browse: 1263 | Download: 1080
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Received |
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2013-10-27 11:56 |
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Peer-Review Started |
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2013-10-28 14:03 |
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To Make the First Decision |
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2013-11-21 20:04 |
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Return for Revision |
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2013-11-22 09:38 |
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Revised |
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2013-11-30 00:36 |
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Second Decision |
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2014-01-08 18:16 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-01-08 18:36 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-02-14 08:24 |
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Publish the Manuscript Online |
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2014-03-06 14:13 |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Topic Highlights |
Article Title |
Systematic review of novel ablative methods in locally advanced pancreatic cancer
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Manuscript Source |
Invited Manuscript |
All Author List |
Margaret G Keane, Konstantinos Bramis, Stephen P Pereira and Giuseppe K Fusai |
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Institutes of Health |
PO1CA84203 |
UCLH/UCL, which receives a proportion of funding from the Department of Health’s National Institute for Health Research Biomedical Research Centres funding scheme |
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CRUK research bursary |
to Keane MG |
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Corresponding Author |
Giuseppe K Fusai, MS, FRCS, HPB and Liver Transplant Unit, Royal Free Hospital, London NW3 2QG, United Kingdom. g.fusai@nhs.net |
Key Words |
Pancreatic cancer; Radiofrequency ablation; Photodynamic therapy; Cryoablation; Microwave ablation; High frequency focused ultrasound; Irreversible electroporation |
Core Tip |
Unresectable locally advanced pancreatic cancer with or without metastatic disease is associated with a very poor prognosis. Current standard therapy is limited to chemotherapy or chemoradiotherapy. Few regimens have been shown to have a substantial survival advantage and novel treatment strategies are urgently needed. Initial studies of ablation in the pancreas were associated with significant morbidity and mortality, which limited widespread adoption. Modifications to the various applications, in particular combining the techniques with high quality imaging such as computed tomography and intraoperative or endoscopic ultrasound has enabled real time treatment monitoring and significant improvements in safety.
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Publish Date |
2014-03-06 14:13 |
Citation |
Keane MG, Bramis K, Pereira SP, Fusai GK. Systematic review of novel ablative methods in locally advanced pancreatic cancer. World J Gastroenterol 2014; 20(9): 2267-2278 |
URL |
http://www.wjgnet.com/1007-9327/full/v20/i9/2267.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v20.i9.2267 |
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