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Articles Published Processes
12/10/2021 7:13:36 AM | Browse: 388 | Download: 896
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Received |
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2021-04-25 06:19 |
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Peer-Review Started |
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2021-04-25 06:22 |
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To Make the First Decision |
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Return for Revision |
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2021-06-04 06:45 |
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Revised |
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2021-06-18 17:10 |
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Second Decision |
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2021-08-30 03:25 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-08-30 06:47 |
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Articles in Press |
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2021-08-30 06:47 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2021-10-14 13:36 |
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Typeset the Manuscript |
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2021-11-30 06:40 |
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Publish the Manuscript Online |
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2021-12-10 07:13 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Serum gastrin-17 concentration for prediction of upper gastrointestinal tract bleeding risk among peptic ulcer patients
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jun-Xian Wang, Yu-Ping Cao, Peng Su, Wei He, Xiao-Ping Li and Ya-Meng Zhu |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Jun-Xian Wang, PhD, Chief Doctor, Department of Gastroenterology, The Second People’s Hospital of Anhui Province, No. 1868 Dangshan Road, Hefei 230011 , Anhui Province, China. ahwjx168@sina.com |
| Key Words |
Peptic ulcer; Upper gastrointestinal bleeding; Gastrin; Pepsinogen; Receiver operating characteristic |
| Core Tip |
Upper gastrointestinal tract bleeding is a severe complication of peptic ulcer that markedly increases mortality. Bleeding risk is elevated by hypersecretion of gastric acid, and secretion rate is associated with serum concentrations of gastrin 17 (G-17), pepsinogen I, and pepsinogen II. Thus, these values may predict bleeding risk among peptic ulcer patients. Indeed, bleeding risk was elevated in patients with G-17 above the normal range (> 15 pmol/L), and serum G-17 > 9.86 pmol/L distinguished bleeding from non-bleeding patients with 90.2% sensitivity and 68.2% specificity. Elevated G-17 may be an effective early predictor of bleeding from peptic ulcer. |
| Publish Date |
2021-12-10 07:13 |
| Citation |
Wang JX, Cao YP, Su P, He W, Li XP, Zhu YM. Serum gastrin-17 concentration for prediction of upper gastrointestinal tract bleeding risk among peptic ulcer patients. World J Clin Cases 2021; 9(35): 10948-10955 |
| URL |
https://www.wjgnet.com/2307-8960/full/v9/i35/10948.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v9.i35.10948 |
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