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12/10/2021 7:13:36 AM | Browse: 263 | Download: 444
Publication Name World Journal of Clinical Cases
Manuscript ID 67358
Country China
Received
2021-04-25 06:19
Peer-Review Started
2021-04-25 06:22
To Make the First Decision
Return for Revision
2021-06-04 06:45
Revised
2021-06-18 17:10
Second Decision
2021-08-30 03:25
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2021-08-30 06:47
Articles in Press
2021-08-30 06:47
Publication Fee Transferred
Edit the Manuscript by Language Editor
2021-10-14 13:36
Typeset the Manuscript
2021-11-30 06:40
Publish the Manuscript Online
2021-12-10 07:13
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright ©The Author(s) 2021. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Observational Study
Article Title Serum gastrin-17 concentration for prediction of upper gastrointestinal tract bleeding risk among peptic ulcer patients
Manuscript Source Unsolicited Manuscript
All Author List Jun-Xian Wang, Yu-Ping Cao, Peng Su, Wei He, Xiao-Ping Li and Ya-Meng Zhu
ORCID
Author(s) ORCID Number
Jun-Xian Wang http://orcid.org/0000-0003-3339-2285
Yu-Ping Cao http://orcid.org/0000-0001-8701-295X
Peng Su http://orcid.org/0000-0002-4637-5049
Wei He http://orcid.org/0000-0002-9962-4627
Xiao-Ping Li http://orcid.org/0000-0003-1496-6159
Ya-Meng Zhu http://orcid.org/0000-0001-8352-0850
Funding Agency and Grant Number
Corresponding Author Jun-Xian Wang, PhD, Chief Doctor, Department of Gastroenterology, The Second People’s Hospital of Anhui Province, No. 1868 Dangshan Road, Hefei 230011 , Anhui Province, China. ahwjx168@sina.com
Key Words Peptic ulcer; Upper gastrointestinal bleeding; Gastrin; Pepsinogen; Receiver operating characteristic
Core Tip Upper gastrointestinal tract bleeding is a severe complication of peptic ulcer that markedly increases mortality. Bleeding risk is elevated by hypersecretion of gastric acid, and secretion rate is associated with serum concentrations of gastrin 17 (G-17), pepsinogen I, and pepsinogen II. Thus, these values may predict bleeding risk among peptic ulcer patients. Indeed, bleeding risk was elevated in patients with G-17 above the normal range (> 15 pmol/L), and serum G-17 > 9.86 pmol/L distinguished bleeding from non-bleeding patients with 90.2% sensitivity and 68.2% specificity. Elevated G-17 may be an effective early predictor of bleeding from peptic ulcer.
Publish Date 2021-12-10 07:13
Citation Wang JX, Cao YP, Su P, He W, Li XP, Zhu YM. Serum gastrin-17 concentration for prediction of upper gastrointestinal tract bleeding risk among peptic ulcer patients. World J Clin Cases 2021; 9(35): 10948-10955
URL https://www.wjgnet.com/2307-8960/full/v9/i35/10948.htm
DOI https://dx.doi.org/10.12998/wjcc.v9.i35.10948
Full Article (PDF) WJCC-9-10948.pdf
Full Article (Word) WJCC-9-10948.docx
Manuscript File 67358_Auto_Edited-JPY-Webster J-Clear.docx
Answering Reviewers 67358-Answering reviewers.pdf
Audio Core Tip 67358-Audio core tip.m4a
Biostatistics Review Certificate 67358-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 67358-Conflict-of-interest statement.pdf
Copyright License Agreement 67358-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 67358-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 67358-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 67358-Language certificate.pdf
Peer-review Report 67358-Peer-review(s).pdf
Scientific Misconduct Check 67358-Bing-Wang LL-2.png
Scientific Misconduct Check 67358-Scientific misconduct check.pdf
Scientific Editor Work List 67358-Scientific editor work list.pdf