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Articles Published Processes
1/20/2022 10:47:59 AM | Browse: 409 | Download: 913
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Received |
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2021-05-05 09:18 |
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Peer-Review Started |
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2021-05-05 09:21 |
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To Make the First Decision |
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Return for Revision |
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2021-06-23 14:53 |
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Revised |
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2021-07-20 12:10 |
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Second Decision |
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2021-12-24 04:48 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2021-12-25 20:00 |
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Articles in Press |
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2021-12-25 20:00 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2022-01-06 08:33 |
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Publish the Manuscript Online |
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2022-01-20 10:47 |
ISSN |
1948-0210 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Cell Biology |
Manuscript Type |
Basic Study |
Article Title |
Therapeutic effects of menstrual blood-derived endometrial stem cells on mouse models of streptozotocin-induced type 1 diabetes
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Manuscript Source |
Invited Manuscript |
All Author List |
Yu-Liang Sun, Ling-Rui Shang, Rui-Hong Liu, Xin-Yi Li, Sheng-Hui Zhang, Ya-Kun Ren, Kang Fu, Hong-Bin Cheng, Badrul Hisham Yahaya, Yan-Li Liu and Jun-Tang Lin |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Henan Province Foundation of China |
202300410307 |
Henan Province Foundation of China |
212102310611 |
Xinxiang City Foundation of China |
GG2020009 |
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Corresponding Author |
Jun-Tang Lin, PhD, Professor, Stem Cell and Biotherapy Technology Research Center, Xinxiang Medical University, East of JinSui Road, Xinxiang 453000, Henan Province, China. linjt@xxmu.edu.cn |
Key Words |
Type 1 diabetes; Menstrual blood-derived endometrial stem cell; Umbilical cord mesenchymal stem cells; Improvement; Complication |
Core Tip |
Mesenchymal stem cell (MSC)-based therapies have resulted in promising improvements for patients with type 1 diabetes (T1D). Menstrual blood-derived endometrial stem cells (MenSC) transplantation has therapeutic effects equal to those of umbilical cord-derived MSC, which can significantly improve the symptoms of streptozotocin-induced T1D mice and exert protective effects on their main organs; MSC-induced angiogenesis, antiapoptotic effects and immunomodulation contribute to these protective effects. The results of this study showed that MenSC are expected to become a promising alternative for clinical diabetes treatment due to their advantages, including their regular and noninvasive collection protocol, abundant availability, and superior proliferative capacity. |
Publish Date |
2022-01-20 10:47 |
Citation |
Sun YL, Shang LR, Liu RH, Li XY, Zhang SH, Ren YK, Fu K, Cheng HB, Yahaya BH, Liu YL, Lin JT. Therapeutic effects of menstrual blood-derived endometrial stem cells on mouse models of streptozotocin-induced type 1 diabetes. World J Stem Cells 2022; 14(1): 104-116 |
URL |
https://www.wjgnet.com/1948-0210/full/v14/i1/104.htm |
DOI |
https://dx.doi.org/10.4252/wjsc.v14.i1.104 |
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