Publication Name	World Journal of Gastroenterology
Manuscript ID	6776
Country	France

Received	2013-10-29 09:07
Peer-Review Started	2013-10-29 22:01
To Make the First Decision	2013-12-26 11:37
Return for Revision	2013-12-27 14:45
Revised	2014-01-12 22:49
Second Decision	2014-04-16 11:26
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-04-16 12:08
Articles in Press	2014-05-23 10:27
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-08-06 08:58
Publish the Manuscript Online	2014-08-20 18:38

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Role of endoscopic ultrasound in the molecular diagnosis of pancreatic cancer
Manuscript Source	Invited Manuscript
All Author List	Barbara Bournet, Marion Gayral, Jérôme Torrisani, Janick Selves, Pierre Cordelier and Louis Buscail
Funding Agency and Grant Number
Corresponding Author	Louis Buscail, MD, PhD, Department of Gastroenterology, CHU Toulouse Rangueil, University of Toulouse, 1 avenue Jean Poulhès, TSA 50032, 31059 Toulouse, France. buscail.l@chu-toulouse.fr
Key Words	Pancreatic ductal adenocarcinoma; Endoscopic ultrasound-guided fine-needle aspiration; Solid pancreatic mass; KRAS-mutation assay; qPCR analysis; Micro-RNA; Chronic pancreatitis
Core Tip	This review depicts the widespread potential for the molecular analysis of samples obtained by ultrasound-guided fine needle aspiration in assessing diagnosis or prognosis of pancreatic adenocarcinoma, as well as translational studies on new markers and epigenetic alterations. Among these markers, Kras oncogene assay appears now the most robust for improvement of positive and differential diagnosis of pancreatic cancer. Clinical implication of miRNA, Mucins and markers of invasion is still debated. Future molecular developments may open windows towards personalized treatments after molecular characterization of a single patient.
Publish Date	2014-08-20 18:38
Citation	Bournet B, Gayral M, Torrisani J, Selves J, Cordelier P, Buscail L. Role of endoscopic ultrasound in the molecular diagnosis of pancreatic cancer. World J Gastroenterol 2014; 20(31): 10758-10768
URL	http://www.wjgnet.com/1007-9327/full/v20/i31/10758.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i31.10758

Full Article (PDF)	WJG-20-10758.pdf
Full Article (Word)	WJG-20-10758.doc
Manuscript File	6776-Review.docx
Answering Reviewers	6776-Answering reviewers.pdf
Copyright License Agreement	6776-Copyright assignment.pdf
Peer-review Report	6776-Peer review(s).pdf
Scientific Editor Work List	6776-Scientific editor work list.doc