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9/10/2014 7:22:00 PM | Browse: 924 | Download: 728
Publication Name World Journal of Hepatology
Manuscript ID 6786
Country South Korea
Received
2013-10-29 09:46
Peer-Review Started
2013-10-30 10:44
To Make the First Decision
2013-12-25 18:00
Return for Revision
2013-12-30 15:49
Revised
2014-01-09 13:29
Second Decision
2014-03-04 09:59
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-03-04 10:30
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-05-08 20:34
Publish the Manuscript Online
2014-05-20 15:05
ISSN 1948-5182 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Pathology
Manuscript Type Review
Article Title Mechanisms of fibrogenesis in liver cirrhosis: The molecular aspects of epithelial-mesenchymal transition
Manuscript Source Invited Manuscript
All Author List Sun-Jae Lee, Kyung-Hyun Kim and Kwan-Kyu Park
Funding Agency and Grant Number
Funding Agency Grant Number
National Research Foundation of Korea 2012R1A1A401015639
Corresponding Author Kwan-Kyu Park, MD, PhD, Department of Pathology, Catholic University of Daegu, College of Medicine, 3056-6 Daemyung 4-Dong, Nam-Gu, Daegu, 705-718, South Korea. kkpark@cu.ac.kr
Key Words Epithelial-mesenchymal transition; Liver; Fibrosis; Transforming growth factor-beta1; Biological markers
Core Tip The cause of fibrosis and diminished regeneration, especially in liver cirrhosis, is still unknown. Epithelial-mesenchymal transition (EMT) has been found to be associated with liver fibrosis. The possibility that EMT could contribute to hepatic fibrogenesis reinforced the concept that activated hepatic stellate cells are not the only key players in the hepatic fibrogenic process. The aim of this article is to describe how EMT participates to hepatic fibrosis and discuss the evidence of supporting this possibility in order to reach reasonable and useful conclusions.
Publish Date 2014-05-20 15:05
Citation Lee SJ, Kim KH, Park KK. Mechanisms of fibrogenesis in liver cirrhosis: The molecular aspects of epithelial-mesenchymal transition. World J Hepatol 2014; 6(4): 207-216
URL http://www.wjgnet.com/1948-5182/full/v6/i4/207.htm
DOI http://dx.doi.org/10.4254/wjh.v6.i4.207
Full Article (PDF) WJH-6-207.pdf
Full Article (Word) WJH-6-207.doc
Manuscript File 6786-Review.docx
Answering Reviewers 6786-Answering reviewers.pdf
Copyright License Agreement 6786-Copyright assignment.pdf
Peer-review Report 6786-Peer review(s).pdf
Scientific Editor Work List 6786-Scientific editor work list.doc