Publication Name	World Journal of Gastroenterology
Manuscript ID	6788
Country	Canada

Received	2013-10-29 09:52
Peer-Review Started	2013-10-30 10:47
To Make the First Decision	2013-11-21 20:50
Return for Revision	2013-11-22 16:22
Revised	2013-12-27 00:20
Second Decision	2014-01-05 14:59
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-01-05 15:16
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-02-16 14:13
Publish the Manuscript Online	2014-03-06 14:13

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Celiac plexus neurolysis in the management of unresectable pancreatic cancer: When and how?
Manuscript Source	Invited Manuscript
All Author List	Jonathan M Wyse, Yen-I Chen and Anand V Sahai
Funding Agency and Grant Number
Corresponding Author	Jonathan M Wyse, MD, MSc, Division of Gastroenterology, Jewish General Hospital, McGill University, 3755 Chemin de la Cote-Ste-Catherine, Montreal H3T 1E2, Quebec, Canada. jonathan.wyse@mcgill.ca
Key Words	Celiac plexus neurolysis; Endoscopic ultrasound; Pancreatic cancer; Pain; Opioid; Gastrointestinal endoscopy
Core Tip	The efficacy of salvage celiac plexus neurolysis (CPN) either by percutaneous or endoscopic ultrasound (EUS) guided technique has been modest in its ability to reduce pain and narcotic requirements in patients with unresectable pancreatic cancer, and few studies with rigorous methodology exist. Data for early EUS-CPN at time of diagnosis appears to prevent pain escalation while moderating narcotic use and future studies should explore CPN for patients before rescue therapy is needed. Reports of serious and fatal complications of CPN have surfaced in recent years.
Publish Date	2014-03-06 14:13
Citation	Wyse JM, Chen YI, Sahai AV. Celiac plexus neurolysis in the management of unresectable pancreatic cancer: When and how? World J Gastroenterol 2014; 20(9): 2186-2192
URL	http://www.wjgnet.com/1007-9327/full/v20/i9/2186.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i9.2186

Full Article (PDF)	WJG-20-2186.pdf
Full Article (Word)	WJG-20-2186.doc
Manuscript File	6788-Review.docx
Answering Reviewers	6788-Answering reviewers.pdf
Copyright License Agreement	6788-Copyright assignment.pdf
Peer-review Report	6788-Peer review(s).pdf
Scientific Editor Work List	6788-Scientific editor work list.doc